Protein Info for Ac3H11_1209 in Acidovorax sp. GW101-3H11

Annotation: Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 PF03710: GlnE" amino acids 68 to 253 (186 residues), 169.1 bits, see alignment E=1.8e-53 amino acids 538 to 780 (243 residues), 200.5 bits, see alignment E=4.6e-63 PF08335: GlnD_UR_UTase" amino acids 286 to 427 (142 residues), 101.5 bits, see alignment E=6.2e-33 amino acids 801 to 887 (87 residues), 21.4 bits, see alignment E=3.2e-08

Best Hits

KEGG orthology group: K00982, glutamate-ammonia-ligase adenylyltransferase [EC: 2.7.7.42] (inferred from 83% identity to dia:Dtpsy_3369)

Predicted SEED Role

"Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42)" in subsystem Ammonia assimilation (EC 2.7.7.42)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.42

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165LBL3 at UniProt or InterPro

Protein Sequence (921 amino acids)

>Ac3H11_1209 Glutamate-ammonia-ligase adenylyltransferase (EC 2.7.7.42) (Acidovorax sp. GW101-3H11)
LSTMTAPSSDPRCSQPFPEGPLAEHSRFYQRLHRRYAGDLALLPPGFPVLATMEQAYDAL
CARGCDTGTALRMLRQLVMERLIRLDCEAQAPLADITRAVTELAELALDRACRHARRELD
ERHGAPCGPQGQPVQLWIIGMGKLGARELNVSSDIDLIYVYEHDGETAGAEGGRGRISNH
EYFARAVKAIYSLVGDTTEHGFVFRVDLALRPNGNSGPASVSLAALEEYLQIQGREWERF
AWLKSRVVAPRDSIGSPEVQALRGVVLPFVFRRYLDYSVFDALRSLHSQIRDHAAKRSAG
HPERANDVKLSRGGIREIEFTVQLLQVVRGGQFPELRRRPTLDALQRLAHAGLMPQATAD
ALAQAYVFLRRVEHRIQYLDDQQTHVLPTRDDDLAWIAQTLGFKDCCAFLHELDAHRELV
AQEFDTLLGGAGKKQCNGGGCGGPRAAAPPPPELEALLEQLPGGFRERVAEWRSHPRVEG
LRDEARARLFRLVQRTAQWLKEGRVTEEAAVRLANWLEPLLRRESYLALLLERPSVHEQL
LHLLGAAKWPARYLLQHPGVIDELVGDHLLSERFVVADFERELAMRLASLRSTGEDDDET
LLNLLRRAQHAETFRTLARDVERRITVEQVADDLSALADSVLRITSQWCWSRLKNRHRDE
PQFAIIGYGKLGGKELGYGSDLDIVFVFDDDDERAPEVYAAFVRKLINWLTVKTGEGDLY
EIDTALRPNGNSGLLVTSFEAYANYQQQRGSNTAWTWEHQAMTRARFVMGSEALRARFDA
VREAVITSTRDPLALQGEIATMRERVRSAHPAPAGRFDVKHSTGGMVDAEFAVQYLVLSQ
SAAHPELRGNVGNIALLQRAEQVGLLPAGVGMAAADAYRELRRVQHVARLDEAPTQVTPP
ALQAERDAVLALWRAVFGAEA