Protein Info for Ac3H11_1105 in Acidovorax sp. GW101-3H11

Annotation: GGDEF domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 708 transmembrane" amino acids 23 to 46 (24 residues), see Phobius details amino acids 305 to 328 (24 residues), see Phobius details PF02743: dCache_1" amino acids 56 to 286 (231 residues), 75.6 bits, see alignment E=1.2e-24 PF00989: PAS" amino acids 391 to 499 (109 residues), 25.2 bits, see alignment E=4.3e-09 TIGR00229: PAS domain S-box protein" amino acids 392 to 507 (116 residues), 40 bits, see alignment E=3.9e-14 PF13426: PAS_9" amino acids 401 to 502 (102 residues), 46.2 bits, see alignment E=1.4e-15 PF08447: PAS_3" amino acids 417 to 487 (71 residues), 26.1 bits, see alignment E=2.6e-09 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 513 to 687 (175 residues), 121.8 bits, see alignment E=2.3e-39 PF00990: GGDEF" amino acids 515 to 684 (170 residues), 120.6 bits, see alignment E=1.7e-38

Best Hits

KEGG orthology group: None (inferred from 74% identity to vei:Veis_4873)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165J6G6 at UniProt or InterPro

Protein Sequence (708 amino acids)

>Ac3H11_1105 GGDEF domain protein (Acidovorax sp. GW101-3H11)
MTAPAPSAAPDDASGWLVPGTLVLRLMLVAALAVALSGAVAAWLVTRASGQEAVRRVVNQ
QTDEVEVVARLLASKIEQSQKVLRTVAAGITPGMLESPSSLEWLLQQGLPAVQFFDTMQV
ARDNGELRLNLRAGQQQKASELDPAERDALRRTLVDGKPLVSELITGRGGEPRVMFTMPL
HREDGTVLGVVAGALRLQSQSLLPPSMTLPAREDSQLIVFTRDGTILSHSDSSRILGQVR
DEAGLAPVYTRWLTQAQPVVGRGMSHVQPDHIVSMAGMPLPQWIVARVSTSQALLAPLRG
AQREAWWLAVASMLLCMLLAVALMGWMAQPLAQLTHKARQLLKTSTRHQQPPADQDWPRA
GGEVGELVRVFQGLVHQGQQQQQRKDTLDGQFQAVLDSASVGIIISRHGMLDVVGRQACV
MLGYTAQELQGRPARTVYASDADYAQVGERVRSEMAAHGAFDGDICFMRKDGTPVWARVQ
GRGVRPDEMHGGTVWILEDITAAREAQVQHAWERTHDALTQLYNRAAFDERLGLLMAERS
TRQRSTAEDEDGNEPQGDGVVLFLDLDHFTVVNDIAGHDAGDDVLRHVARLLASQVRQIG
WAARLGGDEFAVVLPGCALARGQAVAEQLRVAVHAWEPSYQGRSFTLGVSIGLVVLDASL
QDVPSVLYAADMACYDAKRAGRNRVETRHASQATVSASASGRMALGPV