Protein Info for Ac3H11_1094 in Acidovorax sp. GW101-3H11

Annotation: N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 PF09349: OHCU_decarbox" amino acids 9 to 170 (162 residues), 166.6 bits, see alignment E=1.3e-52 TIGR03164: OHCU decarboxylase" amino acids 17 to 171 (155 residues), 182.1 bits, see alignment E=7.9e-58 TIGR01879: amidase, hydantoinase/carbamoylase family" amino acids 188 to 583 (396 residues), 323.9 bits, see alignment E=1.4e-100 PF04389: Peptidase_M28" amino acids 239 to 321 (83 residues), 24.1 bits, see alignment E=5.6e-09 PF01546: Peptidase_M20" amino acids 256 to 584 (329 residues), 68.7 bits, see alignment E=1.4e-22 PF07687: M20_dimer" amino acids 390 to 489 (100 residues), 23.4 bits, see alignment E=9.9e-09

Best Hits

KEGG orthology group: None (inferred from 83% identity to aaa:Acav_1107)

Predicted SEED Role

"N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87)" in subsystem Hydantoin metabolism (EC 3.5.1.87)

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.87

Use Curated BLAST to search for 3.5.1.87

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165J5Y8 at UniProt or InterPro

Protein Sequence (592 amino acids)

>Ac3H11_1094 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) (Acidovorax sp. GW101-3H11)
MALTLEQLNAASPAEALQLLDGLYEHSPWIAERALAQRPFRSQAHLQHALAQVVRTAGQD
AQLALIRAHPELAGKAMVAKNLTAESTNEQSKAGLTQCTPEEFERIQQLNAAYNERFGFP
FILAVRGPRGTGLPKQAIIDTFARRLDNHPEFELAEALRNIYRIAEIRLNDKFATEPVLG
NDVWDWQEKLAEHSDPGFAEKGQLTVTYLTDAHRACAQRISHWMRDCGFDEVEIDAVGNV
VGRYHPATEGARYLMTGSHYDTVRNGGKYDGRLGIFVPMACVRELHRAGRRLPFGIEVVG
FAEEEGQRYKATFLGSGALIGDFNPAWLDQKDVDGVTMRAAMQHAGLCIDDIPKLQRDPA
QYLGFIEVHIEQGPVLNELDLPLGVVTSINGSVRFLCEMIGTASHAGTTPMDRRRDAAVA
VAELALYVEQRAAQDGDSVGTIGQLQVPAGSINVVPGRCQFSLDLRAPTDAQRNALVSDV
KEQLAKIAARRGLRYTLEESMRAAAAPSAPAWQHHWERAVDALGVPVFRMPSGAGHDAMK
LHEIMPQAMLFVRGLNSGISHNPLESTTNNDMQLAVDAFTQVLRQLAEEQQP