Protein Info for Ac3H11_108 in Acidovorax sp. GW101-3H11

Annotation: Hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 PF00702: Hydrolase" amino acids 24 to 213 (190 residues), 73.8 bits, see alignment E=3.9e-24 PF13419: HAD_2" amino acids 124 to 219 (96 residues), 39.3 bits, see alignment E=1.1e-13 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 125 to 213 (89 residues), 46 bits, see alignment E=7.5e-16 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 128 to 219 (92 residues), 33 bits, see alignment E=6.1e-12 PF13242: Hydrolase_like" amino acids 174 to 242 (69 residues), 35.2 bits, see alignment E=1.4e-12

Best Hits

KEGG orthology group: K07025, putative hydrolase of the HAD superfamily (inferred from 70% identity to adk:Alide2_2121)

Predicted SEED Role

"Hydrolase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A165I0D9 at UniProt or InterPro

Protein Sequence (248 amino acids)

>Ac3H11_108 Hydrolase (Acidovorax sp. GW101-3H11)
MTAPQPQPTAPAQASAPQLDIARIRAISIDLDDTLWPIWPTITRAERVLLDWLTHHAPAT
AALFSSTESLRAIRNQMVALRPDLLHDLSALRRESIRLALTQAGDEPALAEPAFDLFFAE
RMRVELFDDAHDALAFLSARYPVVAVSNGNADVHRIGIGHYFRHSISASEFGVAKPDARI
FHAAATAADVLPHEVLHVGDDATLDAQGALNAGMQAVWINSANHPWPHDDVQPHATVDSL
TALCRLLA