Protein Info for AZOBR_RS30760 in Azospirillum brasilense Sp245

Annotation: purine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 20 to 48 (29 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 84 to 102 (19 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 137 to 161 (25 residues), see Phobius details amino acids 173 to 190 (18 residues), see Phobius details amino acids 199 to 221 (23 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 323 to 342 (20 residues), see Phobius details amino acids 351 to 372 (22 residues), see Phobius details amino acids 384 to 404 (21 residues), see Phobius details amino acids 411 to 433 (23 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 16 to 431 (416 residues), 402.8 bits, see alignment E=1.8e-124 PF00860: Xan_ur_permease" amino acids 22 to 397 (376 residues), 357 bits, see alignment E=5.4e-111 TIGR03173: xanthine permease" amino acids 25 to 434 (410 residues), 544.3 bits, see alignment E=1.6e-167

Best Hits

Swiss-Prot: 60% identical to UACT_ECOLI: Uric acid transporter UacT (uacT) from Escherichia coli (strain K12)

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 75% identity to azl:AZL_d02140)

MetaCyc: 60% identical to urate:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN-5076; TRANS-RXN0-530

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AZI0 at UniProt or InterPro

Protein Sequence (453 amino acids)

>AZOBR_RS30760 purine permease (Azospirillum brasilense Sp245)
MSSLESPTRPHPVDERLPLLRLLALGMQHVMVMYAGAIAVPLIIGGALKLPKDQIALLIN
ADLFACGIVTLIQTLGFWKFGIRLPVMMGVTFAAVGPMVAMAGNPSLGLLGIYGAVIGAG
VFATLAAPLVGRLLPLFPPVVTGTVIAIIGISLMRVGITWAGGGAGNPNFGDPLYLGVAL
FVLAVILLITKYAKGFWANISVLLGIVAGFALTMVLGLVSFDGVGQAKWVDVIYPFQFGM
PVFEFWSILTMSLVMIVVMIESTGMFLAVGEMVGRPVTPEQLTRGLRTDGLGTLIGGVFN
TFPYTSFSQNVGLVGITGVRSRWVCVAGGVILVAFGLFPKLAHVVASVPTYVLGGAGLVM
FGMVAATGIKILAKVDYTTNRGNIYVVAISISLGMVPLVADKIFQKMPPFLSPLLHSGIL
LGTIAAVLLNLFFNGLGKASSEEFVAAAKTAEA