Protein Info for AZOBR_RS26410 in Azospirillum brasilense Sp245

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 transmembrane" amino acids 16 to 40 (25 residues), see Phobius details amino acids 52 to 74 (23 residues), see Phobius details amino acids 85 to 105 (21 residues), see Phobius details amino acids 148 to 169 (22 residues), see Phobius details amino acids 184 to 205 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 11 to 107 (97 residues), 75.2 bits, see alignment E=2.4e-25 PF00528: BPD_transp_1" amino acids 31 to 212 (182 residues), 63.2 bits, see alignment E=1.4e-21

Best Hits

Swiss-Prot: 32% identical to YCKA_BACSU: Probable amino-acid ABC transporter permease protein YckA (yckA) from Bacillus subtilis (strain 168)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 78% identity to axy:AXYL_04875)

MetaCyc: 35% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"polar amino acid ABC transporter, inner membrane subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AWS6 at UniProt or InterPro

Protein Sequence (216 amino acids)

>AZOBR_RS26410 amino acid ABC transporter permease (Azospirillum brasilense Sp245)
MRSFSLADFLSLLSALQWTGVLVLIALAFGAPLALGLALMRTSARRALRWTATAFLQLVQ
GVPLLGLLMFFYFGMPVFLGVEMPPLVAVGIAMTVYTASFLGEIWRGGIEAVKHEQWEAA
ACLGLSTWHQFRYVIAPQAFRMALPPTVGFLVQLIKGTSLASIVGFVELARAGQLVSAAT
FQPLLVYSIVAAIYFAACLPLTLWARSLEARLNGAR