Protein Info for AZOBR_RS25985 in Azospirillum brasilense Sp245

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 732 PF01627: Hpt" amino acids 4 to 92 (89 residues), 44.4 bits, see alignment E=3.3e-15 PF02895: H-kinase_dim" amino acids 346 to 412 (67 residues), 56.7 bits, see alignment E=5.6e-19 PF02518: HATPase_c" amino acids 463 to 600 (138 residues), 56.5 bits, see alignment E=7.3e-19 PF01584: CheW" amino acids 606 to 731 (126 residues), 63.6 bits, see alignment E=3.2e-21

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase CheA (EC 2.7.3.-)" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (732 amino acids)

>AZOBR_RS25985 histidine kinase (Azospirillum brasilense Sp245)
MSALFEQFVLESRELLEAAGAALLRLERDPADKTAVNDLFRALHTLKGATALFDMAPFTR
MVHAGEDALMAVRDGRAAMSGELADRLLALLDIGSAWVDGLEHSQTLPDDADARAQAQEV
GLRAALGGPAETVRSGTPAGFAWVDELPEADRAKAAGRTVTAIAYAPAEDCFFAGDDPLD
LCRRIPDLLLLRIEAAGAWPALTDLDPYRCALRFRALSGAPKDELTRLFRGVPDQVSLAT
VAMPALAEPASTAAPLATPPSLATAMLWEQARILRLPGSDEEIVARRAAVLRAVRNILAA
EGRVAERPALDRAVEGPADALMRCIESLADGPAAAAPTAPAAPARRALRVDAERMDRLMA
LVGELVVAKGSLPHLAREAQEGRSADALAQSIKEAHGRIDSIVGDLQDAVLRLRLLPLSR
VFDPLPRLVRDTARRLGKSVELHISGGETEADKDILDILGEPLLHLVRNGLDHGIEPPER
RRAAGKPEVAAIRVQAFQDSGGVVVEVSDDGAGIDAAAVRRKAVTQGALTAEQAAALSDA
EALRLIFLPGVSTSETVSDLSGRGVGMDAVRGAVEQAGGRVEVASTPGAGTRFRLVLPLT
MMVTRLVTVETAGALYGFPMTLVTGMQRVPHGAIRRMKHAESVVVQDAVVPLLRLRRLLN
LPEDERVRSGEAVLLVDLGGQPVALVVDAFQERAEVVLKPMTGLLARLRGYAGTAVLGDG
RLLLALNLRELV