Protein Info for AZOBR_RS23755 in Azospirillum brasilense Sp245
Annotation: multidrug transporter AcrB
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 69% identity to rpx:Rpdx1_1181)Predicted SEED Role
"Cobalt-zinc-cadmium resistance protein CzcA" in subsystem Cobalt-zinc-cadmium resistance
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See G8AUS8 at UniProt or InterPro
Protein Sequence (1073 amino acids)
>AZOBR_RS23755 multidrug transporter AcrB (Azospirillum brasilense Sp245) MRLGLSGVLTRTFIRSPLTPLLLLASLAVGAIALRSLPREEEPQISVPMVDILVQADGLK AGDAVELVTRPLEEIVEGIDGVEHTYSQTMDDRVVVTARFLVGTPSDDAILRVHEKVRAS LDRIPLGIPEPLIVGRGINDVAILTLTLSPRAEAAGRWTVNALHGVADDLLGQLTQVEDV GRSFIVGGSPDQIRVEPDPERLALYGVTLNQLVDKVRNANRSFLAGSLRNAGGSLPVVAG QTLQGTADIGLLLVTTRDGRPVYVKDVADVVAGARPDESSAWHLVPDGKGGLVRSPAVTL AIAKRAGANAVTIADRVLARVQAIQAEGLPKDLTLTVTRNYGETANEKVNELLFHLALAT VTIVGLIVLAIGWREGLVTLVVIPTTILLTLFASWLMGYTINRVSLFALIFSIGILVDDA IVVVENIDRHWSMRDGRGKVQAAVEAVAEVGNPTIVATLTVIAALLPMMFVSGLMGPYMS PIPANASAAMAFSFFVAMVLTPWLMLTLRPGETPVDGHGEPDGGRLGRLYRAAARPVVRS KRRAWIFLLAVGMATLASTGLFYSKDVAVKLLPFDNKSELQVVLDLPRGAAPEDTERALF AAARTIADLPELASVQAYAGTASPFTFNGLVRHYYLRDQPEQGDLQVNLAPKGERSRSSH AVALDIRARLSALPLPAGTMLKVVEVPPGPPVLSTLLMEVYGPDAETRRKAALAVEDAFR GVDFIVDVENSIRPTGDRLRFALDRESLEFHGVEEQAVYDTLRALTGGVPVGYSHRGAGR TPIEIAVRMPRSGLFLSERLLATPVPGARGTVELGDLVTMTREPASHTLFRHNGRFAEMV MADLAGRFEAPIYGMLAVQERLDAVDWAAAGLAAAPEIRLHGQPDDQSRPVLLWDGEWEI TYVTFRDMGAAFGVAILGIYLLVVAQFGSFKLPLVILVPVPLTLIGIVLGHWLFGAAFTA TSMIGFIALAGIIVRNSILLVDFIRHLRERGMPLREAVLEAGAIRFKPILLTAVAAMIGA AFILTDPIFQGLAISLLFGLFSSTLLTVLVIPAIHIVLRGDAADRRDRSNLQG