Protein Info for AZOBR_RS22145 in Azospirillum brasilense Sp245

Annotation: IMP dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1114 PF08379: Bact_transglu_N" amino acids 6 to 84 (79 residues), 84.7 bits, see alignment 9.3e-28 PF01841: Transglut_core" amino acids 138 to 246 (109 residues), 58.3 bits, see alignment E=1.3e-19 PF09899: DUF2126" amino acids 276 to 1112 (837 residues), 1386.7 bits, see alignment E=0

Best Hits

Predicted SEED Role

"Large protein containing transglutaminase-like domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8APZ0 at UniProt or InterPro

Protein Sequence (1114 amino acids)

>AZOBR_RS22145 IMP dehydrogenase (Azospirillum brasilense Sp245)
MAIHVALNHKTVYRYDRLVNLGPQIVRLRPAPHCRTPILSYSLRVTPKHHFLNWQQDPQS
NYQARFVFPEKTREFVIEVDLVAEIAAINPFDFFLEEKAQTIPFAYEPWLERELRPYLEV
EEPGPLLADYMTGISREPAASINFLVDVNQRLQKDIGYVIRLEPGIQTCEETLGKRTGSC
RDSAWLLVQILRNLGLAARFVSGYLIQLTADQKALDGPSGPEEDFTDLHAWTEVFLPGAG
WVGLDPTSGLLAGEGHIPLACTPDASSAAPISGLIDECEVEFGHEMSVTRIYEAPRVTKP
YTPRQWAGIEALGHRIDEELTAGDVRLTMGGEPTFVSIDDMDGAEWNTTALGPNKRKMAA
DLVHRLANRFAPGGLLHFGQGKWYPGESLPRWAMTVYWRRDGEALWANSDLLAREDTDYG
HTAEDAGAFLVTLAKKLGLDPALVLAAYEDPWHYLRRESLLPVNVDPLDSKLEDKEERAR
LAHVFTRGLNEPVGFALPINRKMTQQGPVWLSSAWPLRQERLLLMPGDSPVGYRLPLGSL
PWVAPQDYPYSWETDPFEERAPLPPNRVPLRQHAIREEAGRQDASRRTERVQRAMAEVRS
EMPEHGKSAWWVVRTALTCEARNGRIHLFLPPMNTLEDYLAMLAEIEATALELDMPVVIE
GYQPPKDPRLNSLAVTPDPGVIEVNIHPSHNWDELVRNTLELYEDARQSRLGAEKFMIDG
RHCGTGGGNHVVMGGATAADSPFLRRPDTLRSLITFWQNHPSLSYAFSGLFIGPTSQAPR
VDEARDDALYELEIAFNQIDKAAATGDCPPWMVDRVLRNLLTDVQGNTHRAEFCIDKLYS
PDSSTGRLGLVEFRAFEMPPHAEMSLTQQLLLRALVARFWKAPYKGKLVRWGTELHDRFM
LPYFVQQDLADVIADLRDHGYPIEERWFDPHMNFRFPVYGHVNQRGISLELRMALEPWNV
LGEEPGGGGTVRYVDSSVERVQVRVTGLTDARYAITCNGRRVPLIPTGTEGEFVAGVRYR
AWQPPSCLHPTIPVHTPLVFDILDLWAGRSIGGCTYHVMHPGGRNYDTFPVNANEAEGRR
LARFFPFGHTPGPMDAPAEERNPQFPMTLDLRRG