Protein Info for AZOBR_RS21065 in Azospirillum brasilense Sp245

Annotation: amidohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF07969: Amidohydro_3
  • amino acids 51 to 136 (86 residues), 30 bits, E=3.9e-11
  • amino acids 111 to 383 (273 residues), 71.2 bits, E=1.3e-23
• PF01979: Amidohydro_1
  • amino acids 57 to 398 (342 residues), 48.8 bits, E=6.5e-17

Best Hits

KEGG orthology group: K01485, cytosine deaminase [EC: 3.5.4.1] (inferred from 59% identity to bja:bll3847)

Predicted SEED Role

"Cytosine deaminase (EC 3.5.4.1)" (EC 3.5.4.1)

MetaCyc Pathways

• pyrimidine nucleobases salvage II (2/2 steps found)
• pyrimidine ribonucleosides salvage III (1/2 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Pyrimidine metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.5.4.1

Use Curated BLAST to search for 3.5.4.1

Sequence Analysis Tools

See G8APA5 at UniProt or InterPro

Protein Sequence (415 amino acids)

>AZOBR_RS21065 amidohydrolase (Azospirillum brasilense Sp245)
MTQNQIFDLLLRNARLRGGQGLQDIAVRQGRIAAISPALAGTAVVEAVVEEDAGGRLVLP
GLVDTHIHLDKSCLLCRCRDAGGGLKGAIAAVSRLKRDFTIEDVYERGARTLERAITQGT
MHMRTHVELDPLVGLRSFEAMKRLKRDYAFAIDLSICVFPQEGMTHDPAIERLLAQALAE
GADLLGGCPYTDADPSLQMERIFALAVAHDVDLDFHLDFDLDPSWSHLEEICRRTMAAGW
HGRVAVGHATKLAAIDDAALERMIALLADAGVGVTALPATDLYLNGRDANHRAPRGVAPV
HRLAEGGVAVSVATNNVLNPFTPFGDGSLIRMGNLYANLMHLGPESFGRCLDLISNGAAR
LMRIADYGVAVGGQADMIVLDADDEADAFGGIAVPLMGFKRGRKSFVRPAATLLR