Protein Info for AZOBR_RS19845 in Azospirillum brasilense Sp245

Annotation: MerR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 140 TIGR02044: Cu(I)-responsive transcriptional regulator" amino acids 1 to 126 (126 residues), 170.8 bits, see alignment E=6.5e-55 PF13411: MerR_1" amino acids 1 to 66 (66 residues), 63.7 bits, see alignment E=2e-21 PF00376: MerR" amino acids 2 to 39 (38 residues), 58 bits, see alignment E=9.5e-20 PF09278: MerR-DNA-bind" amino acids 46 to 108 (63 residues), 70.4 bits, see alignment E=2.5e-23

Best Hits

Swiss-Prot: 62% identical to HMRR_SINMW: HTH-type transcriptional regulator HmrR (hmrR) from Sinorhizobium medicae (strain WSM419)

KEGG orthology group: None (inferred from 85% identity to azl:AZL_a03860)

Predicted SEED Role

"Cu(I)-responsive transcriptional regulator" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8ATN6 at UniProt or InterPro

Protein Sequence (140 amino acids)

>AZOBR_RS19845 MerR family transcriptional regulator (Azospirillum brasilense Sp245)
MTIGDAAKASGVNAKLIRYYESIGLIPEAGRTASGYRVYSPSDVNILRFVKRARTLGFSI
ERIQILVGLWQDRSRSSAEVKRVALDHVAELEAKIAELRAMSDTLKHLAHACHGDERPDC
PILRDLEEGGECCHGAERDQ