Protein Info for AZOBR_RS19235 in Azospirillum brasilense Sp245

Annotation: actetate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 41 to 59 (19 residues), see Phobius details amino acids 81 to 104 (24 residues), see Phobius details amino acids 110 to 128 (19 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details amino acids 218 to 238 (21 residues), see Phobius details amino acids 268 to 292 (25 residues), see Phobius details amino acids 304 to 329 (26 residues), see Phobius details amino acids 362 to 390 (29 residues), see Phobius details amino acids 411 to 430 (20 residues), see Phobius details amino acids 436 to 460 (25 residues), see Phobius details amino acids 468 to 491 (24 residues), see Phobius details amino acids 505 to 523 (19 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 69 to 475 (407 residues), 209.8 bits, see alignment E=3.8e-66 PF00474: SSF" amino acids 69 to 475 (407 residues), 389.4 bits, see alignment E=1e-120

Best Hits

Swiss-Prot: 66% identical to ACTP_PECAS: Cation/acetate symporter ActP (actP) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K14393, cation/acetate symporter (inferred from 74% identity to rsq:Rsph17025_3675)

MetaCyc: 66% identical to acetate/glycolate:cation symporter (Escherichia coli K-12 substr. MG1655)
RXN0-1981; RXN0-5111; TRANS-RXN0-576

Predicted SEED Role

"Acetate permease ActP (cation/acetate symporter)" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AT99 at UniProt or InterPro

Protein Sequence (556 amino acids)

>AZOBR_RS19235 actetate permease (Azospirillum brasilense Sp245)
MSAARLLAAASAALLPVLVAGPVHAAAIDGAVERQPVNVTAIAMFLLFVAGTLGITYWAS
KRTRSASDFYTAGGGISGFQNGLAIAGDYMSAAAFLGLSGMVFAKGFDGVIYTIGFLVGW
PLMLFLIAERLRNLGRFTFADVASYRLGQTPIRSLAAVGSLTVVCFYLIAQMVGAGKLIQ
LLFGLDYTYAVVMVGVLMILYVTFGGMLATTWVQIIKAVMLLGGCTVLVGLALAQFGFNP
ERLLQQAVAAHAANAAILRPSAAMADPIAAVSLSLALMCGPAGLPHILMRFFTVPDAKEA
RKSVVYATGFIGYFFILTVTIGFLAIVIVGTNPAYLDAAGKILGGGNMAAIHLSKAIGGN
LFLGFISAVAFATILAVVAGLTLAGASAVSHDLYARVLKKGNATEASEMRVSRLATLALG
VIAITLGLLFENQNIAFMVGLAFGLAASVNFPVLILSIFWKGLTTRGAFIGGFAGLVSCV
AFVVLGPTVWVSVFKFPAPIFPYEHPALFSMVIAFATTWLFSVTDRSARAAAEAKAYEYQ
YIRSETGLGAASAASH