Protein Info for AZOBR_RS11370 in Azospirillum brasilense Sp245

Annotation: preprotein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 transmembrane" amino acids 27 to 45 (19 residues), see Phobius details amino acids 80 to 102 (23 residues), see Phobius details amino acids 123 to 145 (23 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 189 to 208 (20 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 320 to 342 (23 residues), see Phobius details amino acids 373 to 396 (24 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 24 to 432 (409 residues), 424.3 bits, see alignment E=2.5e-131 PF00344: SecY" amino acids 80 to 421 (342 residues), 392.6 bits, see alignment E=6.8e-122

Best Hits

Swiss-Prot: 57% identical to SECY_ECO57: Protein translocase subunit SecY (secY) from Escherichia coli O157:H7

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 90% identity to azl:AZL_006010)

MetaCyc: 57% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8ANK5 at UniProt or InterPro

Protein Sequence (446 amino acids)

>AZOBR_RS11370 preprotein translocase subunit SecY (Azospirillum brasilense Sp245)
MASAAEQLAANINFGAFSKATELKKRIWFTLGALIIYRLGTYIPIPGVNPQILADIFRQQ
GGGILGMFDMLAGGALHRMTIFALNIMPYISASIIVQLLTAVSPQMEALKKEGESGRKKL
NQYTRYGTVLLATVQAWGLAVGLEAMTGASGAAVPEPGLFFKIATVITLVGGTMFLMWLG
EQITARGIGNGISLIIFAGIVAELPRALVSTLELGRTGALSTLFIVFLLLMAVGVVFFIV
FMERAQRRLLIQYPKRQMGNRVFGGEASHLPLKLNTSGVIPPIFASSLLLLPLTAVGFAG
GEGPEWLQTVTRYLAHGTPLYMILYSALIIFFCFFYTAIVFNPADTAENLRKYGGFIPGI
RPGKNTADYIDYVLTRLTVIGSAYLVAVCLLPEILISQHSVPFYFGGTSLLIVVTVTMDT
VAQIHSHLLAHQYEGLIKKAKLRGRK