Protein Info for AZOBR_RS05830 in Azospirillum brasilense Sp245

Annotation: Rrf2 family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 160 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details TIGR00738: Rrf2 family protein" amino acids 1 to 133 (133 residues), 143.5 bits, see alignment E=1.7e-46 PF02082: Rrf2" amino acids 3 to 134 (132 residues), 135.2 bits, see alignment E=1.6e-43

Best Hits

Swiss-Prot: 54% identical to Y379_HAEIN: Putative HTH-type transcriptional regulator HI_0379 (HI_0379) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K13643, Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor (inferred from 94% identity to azl:AZL_020080)

Predicted SEED Role

"Iron-sulfur cluster regulator IscR" in subsystem Rrf2 family transcriptional regulators

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AJY7 at UniProt or InterPro

Protein Sequence (160 amino acids)

>AZOBR_RS05830 Rrf2 family transcriptional regulator (Azospirillum brasilense Sp245)
MRLSTKGRYAVMAMVDLAATSQGSPVALADIADRQEISLSYLEQLFAKLRKGGLVKSVRG
PGGGYLLAHPADATRVSDIILAVDEPIRTTRCANGTPQGCRTNRSRCLTHDLWEELGNQI
HMYLSSVTVADVVERRIIGTSSLTIRGPQPADEGAAVAAE