Protein Info for AZOBR_RS05055 in Azospirillum brasilense Sp245

Annotation: zinc protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF05193: Peptidase_M16_C" amino acids 197 to 373 (177 residues), 106.5 bits, see alignment E=7.8e-35

Best Hits

Swiss-Prot: 41% identical to Y4WB_SINFN: Uncharacterized zinc protease-like protein y4wB (NGR_a01030) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 73% identity to azl:AZL_007020)

Predicted SEED Role

"ZINC PROTEASE (EC 3.4.99.-)" (EC 3.4.99.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AJG2 at UniProt or InterPro

Protein Sequence (454 amino acids)

>AZOBR_RS05055 zinc protease (Azospirillum brasilense Sp245)
MIVLSKRLMSKRVFGACLFLFAFAITTPAAAIEIKRVVSPGGIEAWLVEDHKVPIIALEW
AFEGAGASDPKGKEGLANLAARTLDEGAGPYDSQAFAARLQDNAIALGYDAGRDGFGGSL
RTLSDRRDEAFELTRLSLAEPRFDAEAVERMRAAVLSSLRRDQADPNYVGRRLFYSTAYP
GHPYGDEIRGTLESLPTITPDDLRGFVKDGFGRDRLVVAAAGDISPEDLGRALDHVFGGL
PATSANAAIPDIEPKGLGETLVATRPTAQTVMLMGQTGLKRADPDWYAATVMNYVLGGGG
FGSRLMEEVREKRGLSYGVYSYLIPMEHSALVMAGGNTVNAKAGQALDIMRQEWKRMADE
GVTEEELADAKTYLTGSFPLQLSSTQAIAGILLQVKRDELGIDYLDRRDAFINGVTQADV
QRVAKRLLDPNRLLTVLVGRPEGVTATRTIDGGS