Protein Info for AZOBR_RS03870 in Azospirillum brasilense Sp245

Annotation: DNA polymerase III subunit gamma/tau

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 618 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 22 to 382 (361 residues), 421.8 bits, see alignment E=1.3e-130 PF13177: DNA_pol3_delta2" amino acids 40 to 202 (163 residues), 131.2 bits, see alignment E=1.5e-41 PF00004: AAA" amino acids 61 to 196 (136 residues), 37.6 bits, see alignment E=1.2e-12 PF12169: DNA_pol3_gamma3" amino acids 256 to 397 (142 residues), 174.9 bits, see alignment E=3.5e-55 PF12362: DUF3646" amino acids 464 to 577 (114 residues), 135.6 bits, see alignment E=3.7e-43

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 79% identity to azl:AZL_025120)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AIP2 at UniProt or InterPro

Protein Sequence (618 amino acids)

>AZOBR_RS03870 DNA polymerase III subunit gamma/tau (Azospirillum brasilense Sp245)
VTDTTVADASSSVSGTSGGLAYRVLARKYRPKSFAELIGQDALVRTLTNAIHSGRIAQAF
MLTGVRGVGKTTTARIIARALNCTGPDGTGGPTVTPCGVCDNCRAIAEDRHVDVMEMDAA
SHTGVDDIREIIDGVRYAPVSARYKLYIIDEVHMLSKSAFNALLKTLEEPPAHVKFVFAT
TEIRKVPVTVLSRCQRFDLRRVDAQVLKEHFTRITGLEGAGIEPDAAALIARAADGSVRD
GLSLLDQAIALAAGTVTAQQVRDMLGLADRSKVIDLFEAAVSAKPAEAMDLLSDLHRVGA
DPVVILQDLLDLVHNLTRLKVVPDSANDPGLPEAERTRGAALSAKLGMPALTRAWQLLLK
GLGEVQAAPVPQQALEMVIVRLSYAADMPTPGDLIRQFQNLQNGGGQGGQGGGSAPRGPG
GGPVAVGGSAVRAVAQAQPSPQPSPQPVQTVAVAVADEERVAMPRDFRTLVQLFAEKREG
ALYGHLTGSVHLVRLEPGRLELRLTTLAPSTLPNRVGQLLTEWTGQRWVVIVSDAPGEPT
LIQQEQAAQRRALEEAEAHPVVRAVLDAFPGAKITDVRDLKAAVEAEPQVADDGENPDLM
VMQQDDGVYYPLDDEGDF