Protein Info for AZOBR_RS02475 in Azospirillum brasilense Sp245

Annotation: heme A synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 transmembrane" amino acids 23 to 44 (22 residues), see Phobius details amino acids 108 to 126 (19 residues), see Phobius details amino acids 138 to 156 (19 residues), see Phobius details amino acids 171 to 193 (23 residues), see Phobius details amino acids 214 to 236 (23 residues), see Phobius details amino acids 274 to 294 (21 residues), see Phobius details amino acids 305 to 328 (24 residues), see Phobius details amino acids 334 to 351 (18 residues), see Phobius details PF02628: COX15-CtaA" amino acids 24 to 344 (321 residues), 349.5 bits, see alignment E=8.5e-109

Best Hits

Swiss-Prot: 58% identical to CTAA_RHOCS: Heme A synthase (ctaA) from Rhodospirillum centenum (strain ATCC 51521 / SW)

KEGG orthology group: K02259, cytochrome c oxidase subunit XV assembly protein (inferred from 80% identity to azl:AZL_003430)

Predicted SEED Role

"Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA" in subsystem Biogenesis of cytochrome c oxidases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AH42 at UniProt or InterPro

Protein Sequence (361 amino acids)

>AZOBR_RS02475 heme A synthase (Azospirillum brasilense Sp245)
VTDITAPALAGKDVRDPASTRPIAYWLLVCCAMVFAMAVIGAITRLTESGLSMVEWKPLI
GILPPLSEAEWNRVFGLYQTTPEFRIYNAAMDLAAFKQIFWWEWFHRFWGQLIGFVFLIP
FLRFWVNGRIPADLWPKLAGLFLLGGLQGVIGWYMVKSGLVDRPDVSHYRLALHLGTAIV
IYGLLLRTALGILDPLPLAGWATESGRLRKHARWALGLTGVTIVWGAFVAGTDAGLAYNT
FPLMAGHVIPPEVANLTPWWINLFENTAAIQLTHRALALLTGLVVLGLALRVWVARLPGR
AGRVALLTAAMVLVQIGLGIATLLSFVWIPLGAAHQAGAILLVSGLVWLLHELRPVRVPK
R