Protein Info for AZOBR_RS01370 in Azospirillum brasilense Sp245

Annotation: metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 transmembrane" amino acids 33 to 56 (24 residues), see Phobius details PF04228: Zn_peptidase" amino acids 1 to 292 (292 residues), 408.5 bits, see alignment E=9.2e-127

Best Hits

Swiss-Prot: 53% identical to YPFJ_ECOLI: Uncharacterized protein YpfJ (ypfJ) from Escherichia coli (strain K12)

KEGG orthology group: K07054, (no description) (inferred from 59% identity to xau:Xaut_1265)

Predicted SEED Role

"YpfJ protein, zinc metalloprotease superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AFG7 at UniProt or InterPro

Protein Sequence (297 amino acids)

>AZOBR_RS01370 metallopeptidase (Azospirillum brasilense Sp245)
MRWQDGRESENVEDRRGAPGSGGFRTGGIGIPIGRGGIGIGGLAVIVVVSLLLGINPLDL
LQGTAPQDQARYEQSDAPRGGGDDELKRFVSVVLADTEDTWAAQFQQIGRTYQDPALVLF
SGTVDSGCGFAQAAMGPFYCPQDRKVYIDLSFYRDLRDRFRAPGDFAQAYVIAHEVGHHV
QNLLGISDRVQQAQRQAGSQADANGLSVRLELQADCFAGLWANHANRERQIIEPGDVEEA
LTAASAIGDDRLQKQSRGTVTPDSFTHGSSAQRVQWFRKGLERGELNACDTFGAERL