Protein Info for AZOBR_RS00170 in Azospirillum brasilense Sp245

Annotation: 3-phosphoglycerate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 327 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF03401: TctC" amino acids 52 to 286 (235 residues), 165.8 bits, see alignment E=5.7e-53

Best Hits

KEGG orthology group: None (inferred from 68% identity to azl:AZL_006150)

Predicted SEED Role

"Tricarboxylate transport protein TctC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AE80 at UniProt or InterPro

Protein Sequence (327 amino acids)

>AZOBR_RS00170 3-phosphoglycerate dehydrogenase (Azospirillum brasilense Sp245)
MIIRSKFLALATGTLALAMSTTALSTARAAYPEKPITVVVAYDAGGSTDVTARLLAPFIE
KHLGGTRIEVVNKPGAGGEIGFAAIADAAPDGYSIGFCNTPNMVSIPIERQARFSADRLD
ALVNVVDDPGVWSVPGDSTFKTLKDVVEHAKANPNTVTVGTTGVGSDDQLAMLLVQRQAG
VQFTHVPFSGSAANYKAMLAKKIQISGQNLGEGLRGQASDQIRVLGVMSKERWKAAPDIP
TFAEQGYPVLMASLRGVCAPKGLPADVRAKLVDAVTKAATDPEFVAKAEAKETFQPLRVL
GPDAFAAELKQLDTELKSLWQSSPWLK