Protein Info for AZOBR_RS00095 in Azospirillum brasilense Sp245

Annotation: MFS transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 7 to 24 (18 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 75 to 94 (20 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 164 to 183 (20 residues), see Phobius details amino acids 217 to 240 (24 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 282 to 331 (50 residues), see Phobius details amino acids 339 to 362 (24 residues), see Phobius details amino acids 369 to 390 (22 residues), see Phobius details TIGR00710: drug resistance transporter, Bcr/CflA subfamily" amino acids 10 to 383 (374 residues), 313.1 bits, see alignment E=1.9e-97 PF07690: MFS_1" amino acids 18 to 357 (340 residues), 146.5 bits, see alignment E=1.4e-46 PF00083: Sugar_tr" amino acids 45 to 113 (69 residues), 38.6 bits, see alignment E=9.8e-14 PF06609: TRI12" amino acids 49 to 168 (120 residues), 24.3 bits, see alignment E=1.6e-09

Best Hits

KEGG orthology group: K07552, MFS transporter, DHA1 family, bicyclomycin/chloramphenicol resistance protein (inferred from 77% identity to azl:AZL_006220)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8AE64 at UniProt or InterPro

Protein Sequence (394 amino acids)

>AZOBR_RS00095 MFS transporter permease (Azospirillum brasilense Sp245)
MPRPDSLTVRVLLTALVAFGPLSTDLYLPSLPTLVSVFDTDIATVQLTLSVFLAGFAVSQ
LVYGPVSDRFGRRPALLGGILIYLVASAACALTDDIETLIVARFFQALGACCGPVVARAV
VRDVFGRDRAATVLAYMAMAMTLAPAAGPILGGVLTEWFGWRSNFLLLTGFAALILAATW
TLMGETNANRDETALQPGRLLANYALLLRDRGFVGQMLTVAFAYSGIFAFISGSSFVLIG
RLHLTPAQFGGSFAAVVLGYAVGSFFAGRLSARLGGPRMIRTGTAVSLAGGLLGVGLALG
GVLHLAAVVGPVFLFMLGAGLTLPNAMAGAVGPYPMMAGLASSLVGFVQMTVAALIGVVL
GHTHADSQLPMMTAIGLVALGGALAHRLLVSPRA