Protein Info for AO356_29660 in Pseudomonas fluorescens FW300-N2C3

Annotation: IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF09339: HTH_IclR" amino acids 12 to 63 (52 residues), 66.5 bits, see alignment E=2.1e-22 PF01614: IclR" amino acids 130 to 252 (123 residues), 108.5 bits, see alignment E=3.5e-35

Best Hits

Swiss-Prot: 32% identical to PCAR_PSEPU: Pca regulon regulatory protein (pcaR) from Pseudomonas putida

KEGG orthology group: None (inferred from 84% identity to pfl:PFL_2281)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9X656 at UniProt or InterPro

Protein Sequence (258 amino acids)

>AO356_29660 IclR family transcriptional regulator (Pseudomonas fluorescens FW300-N2C3)
MSDNPHPLFNQSLEKGLAVLRAFNAARRTMNLADIAQAADINKSSAQRMIHTLEELGYVR
KHPQTKRFQLTPKVMEIGYNYLAADTLVDVANPFLAELAQATGETTNLTEPDGLDMVYVA
RFVAPKFIPIHMPIGSRIPMYCTGSGRAFLSALPDDELVAALQASERKRHTQYTLTAIDD
IIEQIEATRRRGYATNKEELFLGDMSIAAPIIGSQGLPVAAVHVVVPTSRWSLEEAERKL
APAVIECARAIRSSIRTL