Protein Info for AO356_28870 in Pseudomonas fluorescens FW300-N2C3

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 424 transmembrane" amino acids 22 to 40 (19 residues), see Phobius details amino acids 50 to 72 (23 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 112 to 135 (24 residues), see Phobius details amino acids 147 to 167 (21 residues), see Phobius details amino acids 173 to 193 (21 residues), see Phobius details amino acids 226 to 247 (22 residues), see Phobius details amino acids 259 to 281 (23 residues), see Phobius details amino acids 293 to 310 (18 residues), see Phobius details amino acids 316 to 339 (24 residues), see Phobius details amino acids 351 to 373 (23 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details PF12832: MFS_1_like" amino acids 18 to 385 (368 residues), 60.3 bits, see alignment E=1.8e-20 PF07690: MFS_1" amino acids 24 to 300 (277 residues), 94.4 bits, see alignment E=6.7e-31 amino acids 230 to 408 (179 residues), 51.7 bits, see alignment E=6.7e-18

Best Hits

Swiss-Prot: 56% identical to Y2456_MYCTU: Uncharacterized MFS-type transporter Rv2456c (Rv2456c) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

KEGG orthology group: None (inferred from 96% identity to pba:PSEBR_a2307)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WE48 at UniProt or InterPro

Protein Sequence (424 amino acids)

>AO356_28870 MFS transporter (Pseudomonas fluorescens FW300-N2C3)
MPVEAAVDRNRDRRNNLSLDGLNFFLADVRDGLGPYLAIYLLAVHRWDPASIGVVMTVAA
MAGLVAQAPAGALIDRVRSKRAVVAVAALVVTLGCLVLPFTSSFGLVALTQAIGAVAASV
FAPAIAAISLGITGAKAFTRRTGRNETFNHAGNACAALLAGGFAWLFGPIAVFYLMAAMA
LASIVAVSCVSAEAIDHDVARGLEAGQLVHGPVPSTLRVLLDNRTLLLFAICCGLFHLAN
AAMLPLVSQKLAQANVHLATPLTSACIVAAQLVMVPMAWLVGVKADAWGRKPLLLAGFLI
LPIRGVLYVLSDDPYWLVAVQLLDGIGAGLFGALFPLVVKDLTQGTGRFNVSLGVLSTVF
GLGAALSNSLAGFVVQGAGYSAAFLTLAAIAALAFGLLLAMPETFRPSRVSQADTLAVPD
GGVA