Protein Info for AO356_27515 in Pseudomonas fluorescens FW300-N2C3

Annotation: 4-aminobutyrate aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 39 to 452 (414 residues), 330.6 bits, E=6.1e-103

Best Hits

KEGG orthology group: K00823, 4-aminobutyrate aminotransferase [EC: 2.6.1.19] (inferred from 96% identity to pba:PSEBR_a3056)

Predicted SEED Role

"Succinylornithine transaminase (EC 2.6.1.81)" in subsystem Arginine and Ornithine Degradation (EC 2.6.1.81)

MetaCyc Pathways

• superpathway of L-arginine and L-ornithine degradation (12/13 steps found)
• superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (10/11 steps found)
• L-arginine degradation II (AST pathway) (5/5 steps found)
• 4-aminobutanoate degradation II (2/2 steps found)
• 4-aminobutanoate degradation III (2/2 steps found)
• superpathway of 4-aminobutanoate degradation (2/3 steps found)
• 4-aminobutanoate degradation I (1/2 steps found)
• GABA shunt II (2/4 steps found)
• GABA shunt I (1/4 steps found)
• 4-aminobutanoate degradation V (2/7 steps found)
• nicotine degradation I (pyridine pathway) (7/17 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Arginine and proline metabolism
• Butanoate metabolism
• Glutamate metabolism
• Propanoate metabolism
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.19, 2.6.1.81

Use Curated BLAST to search for 2.6.1.19 or 2.6.1.81

Sequence Analysis Tools

See A0A0N9XFR8 at UniProt or InterPro

Protein Sequence (457 amino acids)

>AO356_27515 4-aminobutyrate aminotransferase (Pseudomonas fluorescens FW300-N2C3)
MSEAKLEALHFADAPRINSTIPGPRTTEALALSARTESMARGGGRMPVAMDRAFGATFKD
ADDNTYIDLSAGVGVSSVGRCHPKVVQAIREQSEVLMHALEVNSTRRTELAAKLSEIAPD
GLRGDCITFFTQSGSDALEAAIKFAKRVTGRHQIIAFHGGYHGVWNASGALTTGTAYRKG
YGAQMGGVIHAPYPYAYRFPFDTTHKSAEQIAGEYVDYLLNTPYTAADDVAAVIVEPVQG
EGGYVPPSPEFLQLLRKACDRSGTLLIVDEVQSGAGRTGKMWAVEHSGVKPDMLTFGKGI
GSDLPMAGLIMRSDLAAAIPDGSMPNTFAANSLSAAVALTNISILQDPELDLLNRAHTLG
LEAQERIRGFGSPLVGEVRGRGLMIGIELVSDPTTKAPLAPEKIGQLMGYLLSHGVLMIP
CGRYSNVMRVMPSLTISRALFFKALDIFGDALDALDA