Protein Info for AO356_26560 in Pseudomonas fluorescens FW300-N2C3

Annotation: Clp protease ClpC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 918 PF02861: Clp_N" amino acids 104 to 149 (46 residues), 22 bits, see alignment 1.1e-07 amino acids 176 to 228 (53 residues), 56.1 bits, see alignment 2.5e-18 PF00004: AAA" amino acids 287 to 420 (134 residues), 56.7 bits, see alignment E=2.8e-18 amino acids 627 to 745 (119 residues), 38.8 bits, see alignment E=9e-13 PF17871: AAA_lid_9" amino acids 428 to 525 (98 residues), 112.2 bits, see alignment E=7.8e-36 PF00158: Sigma54_activat" amino acids 619 to 744 (126 residues), 29.8 bits, see alignment E=3.6e-10 PF07724: AAA_2" amino acids 621 to 790 (170 residues), 224.5 bits, see alignment E=6.1e-70 PF07728: AAA_5" amino acids 626 to 747 (122 residues), 46.2 bits, see alignment E=3.5e-15 PF10431: ClpB_D2-small" amino acids 796 to 875 (80 residues), 79.2 bits, see alignment E=1.5e-25

Best Hits

KEGG orthology group: K03696, ATP-dependent Clp protease ATP-binding subunit ClpC (inferred from 84% identity to reh:H16_B1382)

Predicted SEED Role

"ATP-dependent Clp protease ATP-binding subunit ClpA" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W8T4 at UniProt or InterPro

Protein Sequence (918 amino acids)

>AO356_26560 Clp protease ClpC (Pseudomonas fluorescens FW300-N2C3)
MATLCEICNARPAVARVTVSQNGQARTMSVCDHDYRQLLRHQSMLNPFDSLLGGGVSRFF
DSMGGAKDQGGDDFRLSAQVPRESVDATDAFSSQTLEILQRAGEKAHELNRSDLDTEHLL
YVLADTDVGAALLKELKLSADDIKGYIDQHAQRGTAEVSVDQMTISPRLKKAFNFAFQAS
RDLGHSYVGPEHLLIGLASVPESIAGTLLKKYGVTPEALRQKVVKVVGKGAEDGRVDTPT
GTPTLDKFGRDLTSLAREGKLDPVLGRAQEIENTIEVLARRRKNNPVLIGEPGVGKTAIV
EGLAQRIVKGDVPEILRGRRLVEVNLNSMVAGSKYRGEFEERAKQLLDEVAAKSSELILF
IDELHTIVGAGQGGEEGGLDIANVLKPALARGELSLIGATTLNEYQKHIEKDAALERRFQ
PVLIAEPTVEQTIIILRGLRDKLEAHHQVTFADEAFVAAAELSDRYITSRFLPDKAIDLI
DQAAARVRISSSSRPAGIQELEAEITQLKREQDYASSRKRFDESKGFEERIGQKQAQLGE
ETEAWERKTGSETLEVTLESIAEVLSRLTGIPVTELTQAERQKLLNMEDTLRDRLVGQED
AVLAVSDAVRLSRAGLGQANRPIATFLFLGPTGVGKTELAKALAETVFGDEQSIIRIDMS
EYMERHAVARLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHPDVSNVLLQVFD
DGRLTDGKGRVVDFSNTIIIATSNLGSPVIMENLERPEDARLTDKALRDELMGVLKGHFR
PEFLNRIDDIIVFHALTRDNIRSIVSIQLDRVIRTAAAQNITVKIDGSLIDYLADVGYQP
EFGARELKRQIRQAVETRLAKEMLAGKLEAGDSVELGYDKGRGEVIFSKVAADVPKVSGD
SSPPDQSNDLAPMAETGT