Protein Info for AO356_24520 in Pseudomonas fluorescens FW300-N2C3

Annotation: ArsR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 116 PF12840: HTH_20" amino acids 14 to 62 (49 residues), 33.1 bits, see alignment E=4.4e-12 PF01022: HTH_5" amino acids 16 to 62 (47 residues), 59.6 bits, see alignment E=2.2e-20

Best Hits

Swiss-Prot: 67% identical to ARSR1_PSEPK: Arsenic resistance transcriptional regulator ArsR1 (arsR1) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K03892, ArsR family transcriptional regulator (inferred from 66% identity to pfo:Pfl01_2400)

MetaCyc: 52% identical to DNA-binding transcriptional repressor ArsR (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Arsenical resistance operon repressor" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9X4C7 at UniProt or InterPro

Protein Sequence (116 amino acids)

>AO356_24520 ArsR family transcriptional regulator (Pseudomonas fluorescens FW300-N2C3)
MPDSPNPVDVFKALADDTRTRIALLVAREGELCVCELTAALGLSQPKISRHLAQLRNAGL
LSDRRQGQWVYYRQHPQLPAWVSTMLEQALAASTAWLTADVQRLNAMPDRPVARCC