Protein Info for AO356_24195 in Pseudomonas fluorescens FW300-N2C3

Annotation: galactonate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 508 PF08666: SAF" amino acids 14 to 84 (71 residues), 25.6 bits, see alignment E=2.2e-09 PF04295: GD_AH_second" amino acids 113 to 252 (140 residues), 152.1 bits, see alignment E=1.5e-48 PF20629: GD_AH_C" amino acids 264 to 506 (243 residues), 343 bits, see alignment E=1.2e-106

Best Hits

KEGG orthology group: K01685, altronate hydrolase [EC: 4.2.1.7] (inferred from 92% identity to pba:PSEBR_a2377)

Predicted SEED Role

"Altronate dehydratase (EC 4.2.1.7)" (EC 4.2.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.7

Use Curated BLAST to search for 4.2.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WBW0 at UniProt or InterPro

Protein Sequence (508 amino acids)

>AO356_24195 galactonate dehydratase (Pseudomonas fluorescens FW300-N2C3)
MNPPSSLLVLTPGDDVAVARGDIAEGQSVNADGIRLVARQAIPSGHKIALRPVLAGQRVL
KYGQTIGQATQAIEPGDHVHVHNLDMPANTTEHSVRNVYVPTSLSENPATFEGYVREDGR
VGTRNYIGVISSVNCSATVCKQIANTFSAERLKDFPNVDGVVAITHGSGCGMGAQGEGID
ILKRTLRGYADHANFAGVLLIGLGCEVNQLTPLMNELGDRSAALKASLVIQDEGGTREAV
RRGIAHIEAMLPLVDQCQRTTVAASHLCVGLQCGGSDGYSGITANPALGAAVDLLVQQGG
TAILSETPEIYGAEHLLTARAASADIAAKLMARIHWWEAYVRHNDGDMNNNPSPGNKAGG
ITTILEKSLGAVAKAGATGLMGVYQYAETVDARGLVFMDTPGYDPVSATGQVAGGANLIC
FTTGRGSTYGCKPTPSLKIATNTRLFQRMELDMDFNAGGIVDGVESVAQAGERLFRLMLA
TASGHRTCSEENGLGDNEFLPWQIGAVM