Protein Info for AO356_21390 in Pseudomonas fluorescens FW300-N2C3

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1092 TIGR00229: PAS domain S-box protein" amino acids 43 to 153 (111 residues), 30.5 bits, see alignment E=3.3e-11 amino acids 154 to 278 (125 residues), 49 bits, see alignment E=6.2e-17 amino acids 280 to 407 (128 residues), 24.7 bits, see alignment E=2.2e-09 amino acids 409 to 532 (124 residues), 60.6 bits, see alignment E=1.6e-20 amino acids 533 to 656 (124 residues), 76.4 bits, see alignment E=2.1e-25 PF08447: PAS_3" amino acids 53 to 140 (88 residues), 48.7 bits, see alignment E=2.6e-16 amino acids 306 to 393 (88 residues), 40.3 bits, see alignment E=1.1e-13 PF00989: PAS" amino acids 159 to 246 (88 residues), 29.9 bits, see alignment E=1.7e-10 amino acids 538 to 647 (110 residues), 37.5 bits, see alignment E=7.4e-13 PF08448: PAS_4" amino acids 419 to 527 (109 residues), 23.3 bits, see alignment E=2.2e-08 amino acids 543 to 648 (106 residues), 25.5 bits, see alignment E=4.6e-09 PF13426: PAS_9" amino acids 422 to 524 (103 residues), 34.6 bits, see alignment E=6.9e-12 amino acids 547 to 648 (102 residues), 41.1 bits, see alignment E=6.4e-14 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 658 to 826 (169 residues), 154.9 bits, see alignment E=1.6e-49 PF00990: GGDEF" amino acids 661 to 822 (162 residues), 163.3 bits, see alignment E=1.4e-51 PF00563: EAL" amino acids 844 to 1081 (238 residues), 250.2 bits, see alignment E=6.5e-78

Best Hits

KEGG orthology group: None (inferred from 97% identity to pba:PSEBR_a3870)

Predicted SEED Role

"Sensory box/GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N7H2N8 at UniProt or InterPro

Protein Sequence (1092 amino acids)

>AO356_21390 histidine kinase (Pseudomonas fluorescens FW300-N2C3)
MPKPADHLPPLPRIQALDPKRSEQSWDSAPQLLAALNGARLGAWSWDIDSGQISWSRGTQ
ALFGFDPRQPLPADVDYLDLLLPEDRARAVRAFHAAVAGAPVEQAMHHRIVWPDGSLHWL
EISGSVLPDKHGRPRMIGVIREITHQREREQALRSSEKRFATLFHLCPNMVLLTRQEDGL
ISEANQYFESLFGWPVHDVIGRTTLELGLWVDPRQRAKLVEATKAKGELVSMEVEFRASN
GQIHSGILSAQKVELEGQPYLLSTFLDTSERKLAEQALKDSQERLDLALDSAQLGTWDWH
IPSGMLYGSARAAQLHGLEPKPFHESFDAFFEGVPTEERNNMRNAYRSLREGPAGNYQLT
YRVQLPDGTSRYLESRARLYRNDDGSPLRMAGTLLDITDQVEREQSLAASEEKFATLFQV
SPDPICVTHQDSGRFLEINSSFTQTFGWTTNDVIGLSADEIGLWGGSGSSLQRIERVIRE
QSLNNVAIVVHHKNGQPLTCVISSRQINVGNQPCIVTTLRDITQQQRSEAALKASEEKFA
KAFHSSPDAITITEHQSGRYLEVNDGFCRLTGYRADEVIGHTVYEVGIWAEEKQRAALLA
ELQLKGRVHHQEMLGRNKRGEILTVEVSVEPITLNETECLLLTARDVSLLRNAEAQIRHL
AYHDSLTNLPNRALLMDRLSQQIALLKRHNLRGALLFLDLDHFKHINDSLGHPVGDTVLK
IITARLEASVRLEDTVARLGGDEFVVLLSGLEGSRSEVSKQVQALADTLRELLSEPMFLD
GQRLQVTPSIGIALIPDHGSTPTDLLKRADIALYRAKDSGRNTSQMFHTTMQKAASERLR
METDLRLALARGEFSVHFQPQVDARDNRIIGAEALVRWHHPDLGAQSPNEFIKVLEDSGL
ILEVGTWILDEACDGFKQLIAKGKIDPQRFSLCVNISPRQFRQSDFVERIENSLAAHGLP
CSLLKLEITEGIVIQNLDDTIAKMRRLKKLGVSFAMDDFGTGYSSLTYLKRLPVDTLKID
QSFVRDATSDPNDAEIIRAIVAMARSLNLVMIAEGVETLEQLHFLQGLDCHLYQGYLHSR
PLPLEAFERLLP