Protein Info for AO356_20510 in Pseudomonas fluorescens FW300-N2C3

Annotation: cytosine methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 283 PF00145: DNA_methylase" amino acids 6 to 169 (164 residues), 170.3 bits, see alignment E=3.9e-54 TIGR00675: DNA (cytosine-5-)-methyltransferase" amino acids 8 to 172 (165 residues), 162.4 bits, see alignment E=1.1e-51

Best Hits

Predicted SEED Role

"DNA-cytosine methyltransferase (EC 2.1.1.37)" (EC 2.1.1.37)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.37

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9XCE0 at UniProt or InterPro

Protein Sequence (283 amino acids)

>AO356_20510 cytosine methyltransferase (Pseudomonas fluorescens FW300-N2C3)
MQQPTIGSLFAGIGGFDVGFENAGYRSAWQVELNPVNRAVLADRFPHARQFEDVRQCGAH
NLSPVDVLTAGFPCQDISIAGCRESNQDTRGLRGERSGLFWEVIRILKEIQPGWVVLENV
VNLLAVNDSQDFETVIRALADCGYVGFWRVLNAQYFGVPQQRRRIFLVAGYRRMPPFEFL
ADAAPVDAIPPASRSIRWPRPADAWAANTLLANKAGSQIAMGCTTFVAHPNGWDQMVERQ
RTSEDDGFCLGLDAANLAEAFSAGNAVVAQVAEWVGRGLIQQR