Protein Info for AO356_13255 in Pseudomonas fluorescens FW300-N2C3

Annotation: multidrug transporter CflA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 51 to 69 (19 residues), see Phobius details amino acids 81 to 100 (20 residues), see Phobius details amino acids 106 to 126 (21 residues), see Phobius details amino acids 138 to 157 (20 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 215 to 239 (25 residues), see Phobius details amino acids 251 to 272 (22 residues), see Phobius details amino acids 282 to 301 (20 residues), see Phobius details amino acids 307 to 328 (22 residues), see Phobius details amino acids 340 to 364 (25 residues), see Phobius details amino acids 370 to 391 (22 residues), see Phobius details PF07690: MFS_1" amino acids 21 to 357 (337 residues), 130.7 bits, see alignment E=6.2e-42 PF00083: Sugar_tr" amino acids 45 to 151 (107 residues), 39.9 bits, see alignment E=2.6e-14

Best Hits

KEGG orthology group: None (inferred from 88% identity to pba:PSEBR_a5354)

Predicted SEED Role

"Multidrug resistance transporter, Bcr/CflA family" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WZ92 at UniProt or InterPro

Protein Sequence (401 amino acids)

>AO356_13255 multidrug transporter CflA (Pseudomonas fluorescens FW300-N2C3)
MTDPQNRLAARKPATVGLLLTLTLLGVFPIDVVLPSFPALSEHFERSSADIALSVSLFAV
GIALSQLLVGPLSDVMGRKNLLLIGIAVSAVGAAGCLLADGYGAFLFLRVVQALGCGCFV
LSQALIQDLFTGREQQRLRIFLVTCGGIFISVSPLAGTGLQSWMGWRGSFLVFIALAIGA
FISACRLLQCPVADSQPRRLDFIASYRKVCGDFSFMAYWLTSALAFSCHFSFIVISPLVL
IDQLRLSPEAFSLALLGYGLAYIGGGAVASVLSNRIDPQTQIITGLALILAAGLLMLGLA
NQLGLSVTTLLLPMIVCTTGTTIARAAAHTQAMNRFPGRAGTSASAGSVLIFIVGGLTSA
AISLTPLDLQLTLALCLVLLSLLGLALNALVRQRDRGLLAG