Protein Info for AO356_12975 in Pseudomonas fluorescens FW300-N2C3

Annotation: multidrug ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 908 transmembrane" amino acids 557 to 577 (21 residues), see Phobius details amino acids 713 to 736 (24 residues), see Phobius details amino acids 763 to 784 (22 residues), see Phobius details amino acids 793 to 815 (23 residues), see Phobius details amino acids 821 to 843 (23 residues), see Phobius details amino acids 881 to 903 (23 residues), see Phobius details PF00005: ABC_tran" amino acids 25 to 173 (149 residues), 96.3 bits, see alignment E=6.5e-31 amino acids 289 to 432 (144 residues), 101.7 bits, see alignment E=1.4e-32 PF13304: AAA_21" amino acids 140 to 197 (58 residues), 32 bits, see alignment 3.2e-11 amino acids 390 to 462 (73 residues), 34.3 bits, see alignment E=6.3e-12 PF12679: ABC2_membrane_2" amino acids 541 to 839 (299 residues), 46.9 bits, see alignment E=6e-16 PF12698: ABC2_membrane_3" amino acids 560 to 900 (341 residues), 158.1 bits, see alignment E=8.5e-50 PF01061: ABC2_membrane" amino acids 711 to 871 (161 residues), 65.8 bits, see alignment E=1.1e-21

Best Hits

Swiss-Prot: 55% identical to RBBA_ECOLI: Ribosome-associated ATPase (rbbA) from Escherichia coli (strain K12)

KEGG orthology group: K13926, ribosome-dependent ATPase (inferred from 92% identity to pba:PSEBR_a5439)

Predicted SEED Role

"ABC-type multidrug transport system, permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WVF8 at UniProt or InterPro

Protein Sequence (908 amino acids)

>AO356_12975 multidrug ABC transporter ATP-binding protein (Pseudomonas fluorescens FW300-N2C3)
MNAGGGEPALRASGLKHRYGAHAALDDIAFNLPVGTRCGLIGPDGAGKSSLLGLIAGVKK
LQHGELDVLGASIEDRHHRNTLYRRIAFMPQGLGGNLYPDLSIRENIRFFATLFGLSRAE
CEQRMGTLLLATDLQRFADRPAGKLSGGMKQKLGLCCALIHEPDLLILDEPTTGVDPLSR
RRFWELIEDVRRQRPQLTLLVATAYMEEAEQFEHCLMLDNGRLIAQGLSADLAAVTPDGK
LDSAFTHFQGDSGHDAEPLTIPPRGDSTADIAIEAHDLTLRFGDFTAVDHVSFAIGRGEI
FGFLGSNGCGKTTTMKVLTGLMPASEGSARLLGNPVNAKDLATRKRVGFMSQSFSLYGEL
SVRQNLTLHAKLFDLPKTESTSRIEDLIQRFQLQDLADQPSGALPLGLRQRLSLAVAVLH
RPEVLILDEPTSGVDPAARDDFWRLLIELSREQGVTIFLSTHFMNEAQRCDRISLMHAGK
VLACDTPAALQAQFNGQTLEAAFVSCLEQAQGEAQQDATPVALDQADTPRDRHGLSLGRL
LAVASREGKELLRDKVRMAFALLGALFMMVIFGYGISLDVEKLAFAVFDQDQSPQSRTYL
EAFRSSRYFEEQPAIRDANELHRRLQRSEIKLALEIPPGFGRDLYAGRQPTVGAWLDGGM
PFRAETSRNYVEAVHLANLEQWAEQSSPARPPHTAAKLETRFRYNQDVVSVNAIGPGVMA
LILAFIPAMLTALGIVREKELGSITNFYATPLTRLEFLLGKQAPYLVVSLVNLALLTAMN
RWLFGVPFKGSGLTLALGGLLYVLATTSMGLLISAFTRTQIAAILGTMIITSLPTIQFSG
LIVPRSSLEGAASVMGQLFPAGHFLDIAVGTFTKALDLRQLWPQCLALFGFFLGFTGLSL
VMLKKQEA