Protein Info for AO356_11955 in Pseudomonas fluorescens FW300-N2C3

Annotation: cobalamin biosynthesis protein CobW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 PF02492: cobW" amino acids 6 to 172 (167 residues), 138.7 bits, see alignment E=8.3e-45

Best Hits

KEGG orthology group: None (inferred from 90% identity to pba:PSEBR_a5604)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WV06 at UniProt or InterPro

Protein Sequence (321 amino acids)

>AO356_11955 cobalamin biosynthesis protein CobW (Pseudomonas fluorescens FW300-N2C3)
MLQHIPTHVIAGPLGAGKTSLIKHLLAQRPANERWAVLINEFGQIGLDAALLTQAGDGIA
LGEVAGGCLCCVNGAPFQIGLGRLLRKARPDRLFIEPSGLGHPAQLMRQLSEAPWLGVLA
VQPCVLVLDARAMADGKPLPDAQRQTLADAGLLVLNKSERLTQADRERVTAQLSGSALYW
TQHGALPIDRLPGLAARGSGSVDNVNLPKSLGQIPAIWTDPTQPICLYQQQDGGWSIGWR
WHPSQRFDAAALTRWLQDQGWKRAKMVIYSRDGWVSANALEGEALGWQTSEWRQDSRVEL
IFHQPQDVDRLKAGLVSCRCS