Protein Info for AO356_05675 in Pseudomonas fluorescens FW300-N2C3

Annotation: damage-inducible protein CinA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 PF02464: CinA" amino acids 5 to 156 (152 residues), 180.1 bits, see alignment E=1.2e-57 TIGR00199: amidohydrolase, PncC family" amino acids 11 to 155 (145 residues), 149.6 bits, see alignment E=3.6e-48

Best Hits

Swiss-Prot: 74% identical to PNCC_PSEPU: Nicotinamide-nucleotide amidohydrolase PncC (pncC) from Pseudomonas putida

KEGG orthology group: K03743, (no description) (inferred from 92% identity to pba:PSEBR_a1122)

Predicted SEED Role

"C-terminal domain of CinA type S; Protein Implicated in DNA repair function with RecA and MutS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9X605 at UniProt or InterPro

Protein Sequence (166 amino acids)

>AO356_05675 damage-inducible protein CinA (Pseudomonas fluorescens FW300-N2C3)
MDDITELAAELGRRLQLLNAHVTTAESCTGGGIAEAITRIPGSSAWFEAGYVTYSNRQKS
QQLEVPAQLFEKVGAVSREVVEAMAQGAQRKSLARFAVAVSGVAGPDGGSPSKPVGTVWL
AWAVGQTLISEQRFFAGNRDEVRRQTVRAALEGLLQHAAVEISNQG