Protein Info for AO353_24675 in Pseudomonas fluorescens FW300-N2E3

Annotation: DNA helicase UvrD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 824 PF00580: UvrD-helicase" amino acids 131 to 299 (169 residues), 35.5 bits, see alignment E=1.4e-12 amino acids 476 to 605 (130 residues), 48.1 bits, see alignment E=2e-16

Best Hits

KEGG orthology group: None (inferred from 87% identity to pfo:Pfl01_2672)

Predicted SEED Role

"UvrD/REP helicase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VYW1 at UniProt or InterPro

Protein Sequence (824 amino acids)

>AO353_24675 DNA helicase UvrD (Pseudomonas fluorescens FW300-N2E3)
VPRHNPDLPSELLPLAEMPLLKRLAARFFGHGLNRLRAQHRASWLHGQADGFRSGHSAGV
DYGYKEGKLDGIEEGRQVLLIRDSRSTEHPAPRIDENLFDDWRLPLSAEIKKRMKADVAR
LLPESAQPSAAQWKMIFSDTPSTSVIAGAGAGKSTTLALRILLLTHYLGFELDSLTVVTF
TRESRKDFINKLIGLFAVWGRALSQKDARDLVRTFHSRILPMVRSLPGFERLQAFENLNG
RSLLDDAEVDSNPFDLRINDTQRQQLNACFHRLFTQSERFRELITPLSRHALQLKELERD
HPDVQKRMAVTELAAKRDEELCDVVEDLWIRAGAWPIKGIEPSRQAFEINGSTFHCHGYI
PTLNAWVVLGFDPRENPQVSRPNAKLTVRAEWAVKRTLFQAFCRKPLIWLDSYESSKRVL
ATLAGDASAGPGFDYKVKGELGSAPLLDCFVAAASFIENLGLDVPAAVGQMSFAKDDPDR
LFFEALSLYWRALEDHLLDQSPPVMTYNRMFALFSEHSPENLKLLSDELLRPMSHLMIDE
FQDVSPQIVSWIRATLMEIRSRGPAMHIGRGAQRSSLLCVGDDWQSIYGWRGSSPKYFME
FNKEFASPATTRVMLSENYRSHQHIIDAAEHIVRAAPAIPGKKAKASGEPGELLPVNVHD
RDDSAMAKRLMEHYRNGDSILMLYRKSSDKSLIEEHISPVVNADSSLPFEARRLKQLTYH
SAKGLQADAVFLLGDCQHLTSSPYKNQVYRMAGLGKDGDAEPYDSAQKDEILRLAYVGIT
RAVKHCYWYVDGQDNQSVNMPKASDRIAQGKPFFADQRVGKQSV