Protein Info for AO353_23675 in Pseudomonas fluorescens FW300-N2E3

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1213 transmembrane" amino acids 1126 to 1143 (18 residues), see Phobius details PF13476: AAA_23" amino acids 6 to 281 (276 residues), 55.8 bits, see alignment E=1.9e-18 PF13555: AAA_29" amino acids 27 to 58 (32 residues), 28.1 bits, see alignment (E = 2.7e-10) PF13304: AAA_21" amino acids 32 to 138 (107 residues), 29.3 bits, see alignment E=1.7e-10 PF13558: SbcC_Walker_B" amino acids 1115 to 1172 (58 residues), 37.1 bits, see alignment 5.8e-13

Best Hits

KEGG orthology group: K03546, exonuclease SbcC (inferred from 78% identity to pfo:Pfl01_3217)

Predicted SEED Role

"Exonuclease SbcC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WKT4 at UniProt or InterPro

Protein Sequence (1213 amino acids)

>AO353_23675 chromosome segregation protein SMC (Pseudomonas fluorescens FW300-N2E3)
MKILAIRLKNLASLAGPFEIDFTAEPLASSGLFAITGPTGAGKSTLLDALCLALFGAVPR
LNNTGRDAKVPDADGEIATGDPRTLLRRGTGDGYAEVDFVGIDGRRYRARWEANRAREKA
NGKLQASRQSLRDLDTDQLLASQKGEYKTQLEAVLGLNFEQFTRAVMLAQSEFSAFLKAD
DNDRSELLEKLTDTALYTRLGKRAFDKSKETREAHKLLQDQATGVTPLEPEARAELDQRF
NDAQQQLKNQQAQLKQLELQNTWLKELQQLQDQQQAAAEQLQQAQQSWDAQTGERLNLAR
LEQLAPQRHQFARQTELSAQLSPLAALIQQHAQQQNELQTRQVQLEHSLESAKTALTQAQ
SQHSNNAPLLRQAFEEQSNLARLTQTINASAELKHNAELASSEGQQAIAQMLEQQQRVAE
RLATIATQLELSLQLAPVSDAWNAYRERLQQLMLVGNRLKKGQAELLQMEQRAADTAAQF
SAQRQSLELLYSEAGAEPAAVAEQIQILGSLLQDNRKQQRAIEELARLWARQQELDTRTQ
DLQQRLQTVQTERERLTREGVQAKAELTVAEQTLTVTRELLERQRLARSASVEELRGQLQ
DDQPCPVCGSVEHPYHQPEALLQSLGRHDESEQANAQKAVDLLKEKLADLRTEVGGLIAQ
QKELLQQQEQLATQQQSLTPSLEAHPLAAQLLTQETAKRDAWLNQQSAQLNQSIAQDEQR
QSALLTLQQDAARLQQQLQAADQASQQAAQQLAIQQRELSNDSQRLEEELAAFSALLPAA
TLDGLRNEPAATFMQLDQQVAQRLEQLELQREELSEQQQRQQTLEKEQDRQLTRVQQLQA
AQLQFSALAEQQHAAQQKLAELLGEQPSAEQWQQQLDQAVEQARQAEAMANQELQEVRSQ
QIQLAAELRAEQQRQHALEAESHELSGKIAEWRALHPELDDGGLEQLLAFSDEQVSQLRQ
QLQLGEKAIEQAKVLVHEREQRLHIHQAQHNGNLDAEQLATALGELQNQFGISEQLCAEL
RAQQAEDQRRQDANQALAQRIGDAYNEWQRWARLNALIGSATGDTFRKIAQAYNLDLLVH
HANAQLRQLVRRYRLKRGGSMLGLLVMDTEMGDELRSVHSLSGGETFLVSLALALGLASM
ASSTLKIESLFIDEGFGSLDPESLQLAMDALDGLQAQGRKVGVISHVQEMHERIPVQIQV
HRQGNGLSTLEVK