Protein Info for AO353_22800 in Pseudomonas fluorescens FW300-N2E3

Annotation: sulfite reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 53 to 109 (57 residues), 59 bits, 3e-20
  • amino acids 343 to 398 (56 residues), 42.5 bits, 4.4e-15
• PF01077: NIR_SIR
  • amino acids 119 to 272 (154 residues), 167.7 bits, E=1.4e-53
  • amino acids 411 to 547 (137 residues), 55.5 bits, E=4.8e-19

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 96% identity to pfo:Pfl01_3112)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (12/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (9/10 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

See A0A0N9VY43 at UniProt or InterPro

Protein Sequence (552 amino acids)

>AO353_22800 sulfite reductase (Pseudomonas fluorescens FW300-N2E3)
MYVYDEYDQRIIEDRVKQFRDQTRRYLAGELSEEEFRPLRLQNGLYIQRFAPMLRVAVPY
GQLTSRQTRMMAKIARDYDKGYAHISTRQNVQFNWPALEDIPDILAELATVQMHAIQTSG
NCLRNVTTDQFAGVAADELIDPRPWCEIVRQWTTFHPEFAYLPRKFKIAINGSTSDRAAI
EVHDIGLEPVHNAAGELGFRVLVGGGLGRTPVVGAFINEFLPWPDLLSYLDAILRVYNRY
GRRDNKYKARIKILVKALTPEVFAQKVDAEMEYLRGGQTTLTEAEVHRVAKHFVDPDYNV
LNDQTAELAELDKQYPGFARWRTRNTLAHKKPGYVAVTLSLKPTGVAPGDLTDKQLDGVA
DLADRYSFGQLRTSHEQNIILADVEQSQLFTLWGELREQGFATPNIGLLTDIICCPGGDF
CSLANAKSIPIAEAIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGILGVDKKGE
EFYQVSLGGSASRDASLGKILGPSFAQDDMPDVISKLIDVYVEQRTEDERFIDTYQRIGI
DLFKERVYAANN