Protein Info for AO353_21835 in Pseudomonas fluorescens FW300-N2E3

Annotation: excinuclease ABC subunit C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 607 TIGR00194: excinuclease ABC subunit C" amino acids 11 to 585 (575 residues), 606.8 bits, see alignment E=2.2e-186 PF01541: GIY-YIG" amino acids 18 to 93 (76 residues), 40.3 bits, see alignment E=9.3e-14 PF02151: UVR" amino acids 206 to 237 (32 residues), 36.8 bits, see alignment (E = 7.2e-13) PF08459: UvrC_RNaseH_dom" amino acids 383 to 538 (156 residues), 183.2 bits, see alignment E=9.5e-58 PF14520: HHH_5" amino acids 553 to 602 (50 residues), 38.1 bits, see alignment 5.3e-13

Best Hits

Swiss-Prot: 96% identical to UVRC_PSEPH: UvrABC system protein C (uvrC) from Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CHA0)

KEGG orthology group: K03703, excinuclease ABC subunit C (inferred from 96% identity to pba:PSEBR_a1985)

Predicted SEED Role

"Excinuclease ABC subunit C" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N7H0M8 at UniProt or InterPro

Protein Sequence (607 amino acids)

>AO353_21835 excinuclease ABC subunit C (Pseudomonas fluorescens FW300-N2E3)
MTDPFDPSAFLSTVSGRPGVYRMFDSDARLLYVGKAKNLKKRLASYFRKTGLAPKTAALV
GRIAQIETTITANETEALLLEQTLIKEWRPPYNILLRDDKSYPYVFLSDGDFPRLSIHRG
AKKLKGKYFGPYPSAGAIRESLSLLQKTFFVRQCEDSYYKNRTRPCLQYQIKRCKAPCVG
LVEPQVYAEDVRHSVMFLEGRSNALTDELSAGMEQAASTLDFERAAELRDQISLLRRVQD
QQSMEGGTGDVDVIAAFINPGGACVHLISVRGGRVLGSKNFFPQVGIEEDVAEVMAAFLG
QYFISSPERDLPSELIVNVVHEDFPTLIAAIEELRGRELTISHRVRGTRARWQQLAVTNA
EQALGARLANRQHVAARFEALAQVLDLDEPPQRLECYDISHSSGEATVASCVVFGPEGPL
KSDYRRYNIEGVTPGDDYAAMHQALTRRFSKLKDGEGKLPDILLVDGGKGQLSMARDVLN
ELAVPDLILLGVAKGATRKAGFETLYLNDAAHEFTLRGDSPALHLIQQIRDEAHRFAITG
HRARRGKTRRTSTLEGVAGVGPTRRRDLLKHFGGLQELSRASIEEIAKAPGISKKLAELI
YANLHSE