Protein Info for AO353_20200 in Pseudomonas fluorescens FW300-N2E3

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 transmembrane" amino acids 12 to 34 (23 residues), see Phobius details PF13624: SurA_N_3" amino acids 1 to 164 (164 residues), 158.1 bits, see alignment E=4.3e-50 PF13623: SurA_N_2" amino acids 2 to 140 (139 residues), 115.8 bits, see alignment E=4.1e-37 PF13145: Rotamase_2" amino acids 245 to 375 (131 residues), 52.3 bits, see alignment E=2.5e-17 PF13616: Rotamase_3" amino acids 253 to 360 (108 residues), 98.6 bits, see alignment E=8.9e-32 PF00639: Rotamase" amino acids 269 to 359 (91 residues), 97.9 bits, see alignment E=1.4e-31

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 90% identity to pba:PSEBR_a1817)

Predicted SEED Role

"Peptidyl-prolyl cis-trans isomerase PpiD (EC 5.2.1.8)" (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VXK9 at UniProt or InterPro

Protein Sequence (619 amino acids)

>AO353_20200 peptidylprolyl isomerase (Pseudomonas fluorescens FW300-N2E3)
MLQNIRDNSQGWIAKTIIGVIVALMALTGFDAIFKATTHRNDAAKVNGEEISQNELSQAV
DMQRRQLMQQLGKDFDASLLDEKMLRDAALKGLIDRKLLLQGAEKSKFAFSEAALDQVIL
QTPEFQVDGKFSPERFDQVIRQLGYSRMQFRQMLAQEMLIGQLRAGLAGSGFVTDAQVQA
FARLEKQTRDFATLNVKADPAAVKLTDEEVKAYYDEHAKEFMTPDQVVIDYLELKKASFF
DQVAVKDEDLQALYQKETANLAEQRRAAHILIEVNDKVNEAQAKAKIEEIQARLAKGESF
EALAKEFSQDPGSAANGGDLGYAGPGVYDPTFEKALYALGKDQVSAPVRTEFGFHLIKLL
GVEAPQVPSFASLKDKLTKELKTQQVEQRFVDATKQLEDAAFEASDLAQPAADLKLTVHT
SAPFGREGGEGIAANRAVVTAAFSPEVLDEGANSTGIELDPETVVVLRAKEHRKPEQLPL
ESVAASIRVQLTKEHASAAAKTKADELIASLRDGKTPLASQGWKVTNAATRAQEGVDPTV
LQALFRMPKPAAKDKPTFSSVTLTDGSLVIVRLNGVSEAAAPSEEEKAQYRRFLASRVGQ
QDFAAYRKQLESQADIKRY