Protein Info for AO353_19670 in Pseudomonas fluorescens FW300-N2E3

Annotation: nicotinamidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 PF00857: Isochorismatase" amino acids 21 to 172 (152 residues), 83.1 bits, see alignment E=1.4e-27

Best Hits

KEGG orthology group: None (inferred from 74% identity to reh:H16_B1921)

Predicted SEED Role

"Nicotinamidase family protein YcaC" in subsystem NAD and NADP cofactor biosynthesis global

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WKR6 at UniProt or InterPro

Protein Sequence (227 amino acids)

>AO353_19670 nicotinamidase (Pseudomonas fluorescens FW300-N2E3)
MSTINAANFNGLKPTIDPNDSALLLIDHQSGLFQIVKDMDVPQLRANAIALAKAATLLKM
PVITTASVPQGPNGPLIPEIHQEAPHARYVARKGEINAWDNPEFHAAVKATGKKTLVIAG
TLTSVCLAFPSIAAVHEGYKVFAVVDASGNHSKLATDLTIARLAQAGVVPIDIMATLSEL
QGSWNRPDAEQWAAVYAQTMPHYQLLIESYLKAQQVANEHEVLDSQR