Protein Info for AO353_19620 in Pseudomonas fluorescens FW300-N2E3

Annotation: methyltransferase type 12

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 PF05891: Methyltransf_PK" amino acids 74 to 251 (178 residues), 32.8 bits, see alignment E=1.8e-11 PF13489: Methyltransf_23" amino acids 90 to 250 (161 residues), 49.1 bits, see alignment E=1.9e-16 PF13847: Methyltransf_31" amino acids 96 to 206 (111 residues), 44.2 bits, see alignment E=6.3e-15 PF02353: CMAS" amino acids 96 to 204 (109 residues), 49.4 bits, see alignment E=1.5e-16 PF13649: Methyltransf_25" amino acids 98 to 200 (103 residues), 57.4 bits, see alignment E=6.9e-19 PF08241: Methyltransf_11" amino acids 99 to 204 (106 residues), 43.7 bits, see alignment E=1.2e-14 PF08242: Methyltransf_12" amino acids 99 to 201 (103 residues), 47.7 bits, see alignment E=7.4e-16

Best Hits

KEGG orthology group: None (inferred from 72% identity to bmj:BMULJ_05582)

MetaCyc: 69% identical to pre-sodorifen synthase (Serratia plymuthica 4Rx13)
RXN-20720 [EC: 2.1.1.363]

Predicted SEED Role

"hypothetical protein; Some similarities with methyltransferase and with fatty acid synthase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.363

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WY92 at UniProt or InterPro

Protein Sequence (318 amino acids)

>AO353_19620 methyltransferase type 12 (Pseudomonas fluorescens FW300-N2E3)
MSSPPQKITLADETRLPYQIIQGSSIDSYQEKVVYTYGDSPEDWRKAIGNYILFQFGVYD
DPRSTPPISLDESGIRYFERQLKLAGLEEPNRPPIKRILDIGCGWGYILKYLAERFPECQ
RLDGVNVSRRQLEHCAKFHAEQGLSERINLYLCNAKDIELLPGADEPYDLVIIRGVISHF
PDELYETTMQALAGRVREGGVVVIADNLYNTPPATYTPDTPDEVDRLACKHRKSPAYFRE
VLEESGFTIHDMRVLPSNIDVARWLMDSKANIENKELFPYGVTGALEELRVLAENWSVAL
IKNKVSTYSVVVKKPKNN