Protein Info for AO353_19270 in Pseudomonas fluorescens FW300-N2E3

Annotation: LuxR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF00072: Response_reg" amino acids 6 to 116 (111 residues), 92.9 bits, see alignment E=1.4e-30 PF00196: GerE" amino acids 154 to 208 (55 residues), 56.7 bits, see alignment E=1.4e-19

Best Hits

Swiss-Prot: 34% identical to LIAR_BACSU: Transcriptional regulatory protein LiaR (liaR) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 91% identity to pfo:Pfl01_3957)

MetaCyc: 36% identical to DNA-binding transcriptional dual regulator NarL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WIP4 at UniProt or InterPro

Protein Sequence (219 amino acids)

>AO353_19270 LuxR family transcriptional regulator (Pseudomonas fluorescens FW300-N2E3)
LTCNLLLVDDHSLIRAGVRALVLDIPGYAVIGEANDGAQLLEMVEKLSPDIILLDISMKE
TGGLEALQRLKAVRPQSKVLILSMHTDPTLIMQALESGAHGYLLKDTTATELEHALEALR
NNERYLSPAIAHTVINQALVRAQKSRPEPVDTHNLTARQLEILRLIVRGKSTREIANGLG
LSIKTVETHRSQIMKRLQIFDVAGLVLFAVREQIISLDD