Protein Info for AO353_19260 in Pseudomonas fluorescens FW300-N2E3

Annotation: molybdenum cofactor biosynthesis protein MoaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 PF03453: MoeA_N" amino acids 14 to 175 (162 residues), 153.5 bits, see alignment E=6.1e-49 TIGR00177: molybdenum cofactor synthesis domain" amino acids 184 to 320 (137 residues), 105 bits, see alignment E=1.8e-34 PF00994: MoCF_biosynth" amino acids 188 to 323 (136 residues), 110.2 bits, see alignment E=1.1e-35 PF03454: MoeA_C" amino acids 338 to 403 (66 residues), 51.4 bits, see alignment E=1.5e-17

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 88% identity to pfl:PFL_4221)

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WF27 at UniProt or InterPro

Protein Sequence (408 amino acids)

>AO353_19260 molybdenum cofactor biosynthesis protein MoaA (Pseudomonas fluorescens FW300-N2E3)
VNPVGKPGKTGSLMPVEVALARLLEMAEASPILERERLPLAAIQGRVLAEDLVSTLDLPP
WPNSAMDGYALRLADWTGEPLVVSQKIFAGQAPEPLAPGTCARIFTGAPVPVGADCVEMQ
ENAEVQADQRVRFTEPMRAGQNIRPQGQETTVGEQVLTAGTRLGPIEQGLAASLGCAELE
VVRKVRVAVLSTGDELVEPGQALGPGQIYNSNRVLLCSWLQRLGCEVIDAGILPDDLQAT
RNRLAELGDVDLILSTGGVSVGEADFLGIALREEGELALWKLAIKPGKPLTFGHFRGVPV
IGLPGNPASTLVTFALLARPYLLRRQGVREVRPLQFQVPAGFVWSKAGNRREYLRGRLEH
GRAIIYKNQSSGVLRSAAWAEGLVEVLEDRTLVEGDWVNFIPLSEVLG