Protein Info for AO353_19235 in Pseudomonas fluorescens FW300-N2E3
Updated annotation (from data): DNA damage response gene with a putative DNA binding domain (PA0922-like)
Rationale: Conserved and specific phenotype: important for resisting cisplatin. Also some homologs are regulated by LexA.
Original annotation: transcriptional regulator
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: None (inferred from 92% identity to pba:PSEBR_a1645)Predicted SEED Role
"Transcriptional regulators"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0N9WY37 at UniProt or InterPro
Protein Sequence (106 amino acids)
>AO353_19235 DNA damage response gene with a putative DNA binding domain (PA0922-like) (Pseudomonas fluorescens FW300-N2E3) MVNVEQLKASVNRMSADVVQEAVLELRLDGLVTEGKTPFNKLHFNTCFAEIEALFQRAGY HRQLDVVGYQGLLYALYDPGRWEAVDVLRWLKEFTEAAAQRVSLTA