Protein Info for AO353_18825 in Pseudomonas fluorescens FW300-N2E3

Annotation: chemotaxis protein CheW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 148 to 170 (23 residues), see Phobius details PF01584: CheW" amino acids 146 to 278 (133 residues), 50.9 bits, see alignment E=6.4e-18

Best Hits

KEGG orthology group: K03408, purine-binding chemotaxis protein CheW (inferred from 82% identity to pba:PSEBR_a1506)

Predicted SEED Role

"CheW domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VX34 at UniProt or InterPro

Protein Sequence (298 amino acids)

>AO353_18825 chemotaxis protein CheW (Pseudomonas fluorescens FW300-N2E3)
MNRPVKITSRPQLALQSYLDALLQDATEELPSEVEVLPEVVEVVEVVEAIEAQGALDEFQ
AAVLEEQARDAQKPVVAPPVVAPVAEAPVVVPVLEAPVPILAPVSTVAPLLKALVEPVVE
VHLPPSNTPPPVVGDDRPSWAAEPFECLLFDVAGLTLAVPLVCLGSIYSLAGHELTPLFG
QPEWFLGILPSQAGNLKVLDTARWVMPDRYRDDFRQGLQYVISVQGYEWGLAVHQVSRSL
RLDPNEIKWRSHRGQRPWLAGTVIEHMCALLDVSELAELIASGGAKHMGGGKPAHKPT