Protein Info for AO353_18265 in Pseudomonas fluorescens FW300-N2E3

Annotation: multidrug ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 40 to 62 (23 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 269 to 292 (24 residues), see Phobius details amino acids 297 to 322 (26 residues), see Phobius details PF00664: ABC_membrane" amino acids 42 to 303 (262 residues), 51.9 bits, see alignment E=9.4e-18 PF00005: ABC_tran" amino acids 379 to 532 (154 residues), 115.6 bits, see alignment E=2.9e-37

Best Hits

Swiss-Prot: 52% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 93% identity to pba:PSEBR_a1402)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9VW97 at UniProt or InterPro

Protein Sequence (610 amino acids)

>AO353_18265 multidrug ABC transporter ATP-binding protein (Pseudomonas fluorescens FW300-N2E3)
MLYRRFEKLIDIFRDAPTAAPPSRVLPFYTYYLRQVWPSFAALLVVGLIGALIEVALFSY
LSRIIDLAQGTPNVDFFKIHGVELAWMAVVALFLRPIFVGLHDLLVHQTLSPGMTSMIRW
QNHSYVLKQSLNFFQNDFAGRIAQRIMQTGNSLRDSAVQAVDALWHVLIYAISSLVLFAE
ADWRLMIPLLTWIACYIGALCYFVPRVKERSVVSSDARSKLMGRIVDGYTNITTLKLFAH
TNFEQQYAREAIAEQTEKSQLAGRVVTSMDVVITSMNGLLIVGTTSLALWLWTQSLISVG
AIALATGLVIRIVNMSGWIMWVVNGIFENIGMVQDGLQTIAQPISVTDRVPAPRLEVARG
EVRFEHVTFHYGKKSGIIDDLNLIIKPGEKIGLIGPSGAGKSTLVNLLLRLYDLQSGQIL
VDGQNIASVAQESLRERIGMITQDTSLLHRSIRDNLLYGKPDATDEELWEAVRKARADEF
IPLLSDAEGRNGFDAHVGERGVKLSGGQRQRIAIARVLLKDAPILIMDEATSALDSEVEA
AIQESLETLMQGKTVIAIAHRLSTIARMDRLVVLEKGHIAETGSHAELLAHGGLYARLWQ
HQTGGFVGID