Protein Info for AO353_17490 in Pseudomonas fluorescens FW300-N2E3

Annotation: cytochrome C oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 transmembrane" amino acids 31 to 53 (23 residues), see Phobius details amino acids 77 to 100 (24 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 161 to 185 (25 residues), see Phobius details amino acids 205 to 231 (27 residues), see Phobius details amino acids 265 to 288 (24 residues), see Phobius details amino acids 300 to 320 (21 residues), see Phobius details amino acids 329 to 351 (23 residues), see Phobius details amino acids 365 to 388 (24 residues), see Phobius details amino acids 401 to 425 (25 residues), see Phobius details amino acids 441 to 461 (21 residues), see Phobius details amino acids 487 to 509 (23 residues), see Phobius details TIGR02891: cytochrome c oxidase, subunit I" amino acids 22 to 544 (523 residues), 677.6 bits, see alignment E=5.5e-208 PF00115: COX1" amino acids 31 to 494 (464 residues), 472.7 bits, see alignment E=5.7e-146

Best Hits

Swiss-Prot: 76% identical to COXN_BRADU: Alternative cytochrome c oxidase subunit 1 (coxN) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K02274, cytochrome c oxidase subunit I [EC: 1.9.3.1] (inferred from 81% identity to rpi:Rpic_4873)

Predicted SEED Role

"Alternative cytochrome c oxidase polypeptide CoxN (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N7H0C9 at UniProt or InterPro

Protein Sequence (591 amino acids)

>AO353_17490 cytochrome C oxidase (Pseudomonas fluorescens FW300-N2E3)
MAYAEQAETEALHEPKSFLTKYIWSQDHKVIAIQYSLTAIFVGIIAVVLSDLMRLQIGFP
GSLGFMDASTYYQAMTMHGMIMVIYLLTALFLGGFGNYLIPLMVGARDMVFPYVNMLSYW
TYLLAVLVLLASFFVSGGPTGAGWTLYPPQSITKGTPGTEWGIVLMLVSLAIFIVATTMG
GLNYVTTVLQARTHGMTLFRMPLSVWGIFMASIMALLAFPALFVSAIMTLFDKLLGTSFF
MPAIISLGQQLDHQGGSPILFQHLFWFFGHPEVYIVALPAFGLVSDLISTHARKGIFGYR
MMVWAIIAIGVLSFVVWAHHMYVSGMNPYFGFFFATTTLIIAVPTALKVYNWILTLWRGD
IHLTVPMLFALAFIVTFLVGGLTGLFLGNVIVDIPLSDTYFVVAHFHMVMGVAPVLVVFG
GIYHWFPKVTGRMTNDTLGKLHFWITFLGTYAIFFPMHYLGFQGMPRRYYAYDNYAFIPQ
SAQELNSFITVVALIVGVSQLLFLFNLAWSTFKGKPAGSNPWGAASLEWQTPDTPPVHGN
WGAKLPVVHRWAYDYSMPGIDQDFVPQTVSDEELEQMRQLSAGASIADVKT