Protein Info for AO353_14840 in Pseudomonas fluorescens FW300-N2E3

Annotation: NAD-dependent dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 TIGR01777: TIGR01777 family protein" amino acids 3 to 293 (291 residues), 361 bits, see alignment E=2.9e-112 PF01370: Epimerase" amino acids 3 to 222 (220 residues), 109.2 bits, see alignment E=3.5e-35 PF08338: DUF1731" amino acids 250 to 296 (47 residues), 65.3 bits, see alignment 5.1e-22

Best Hits

Swiss-Prot: 41% identical to D39U1_MOUSE: Epimerase family protein SDR39U1 (Sdr39u1) from Mus musculus

KEGG orthology group: K07071, (no description) (inferred from 86% identity to pfo:Pfl01_4731)

Predicted SEED Role

"Cell division inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WDB8 at UniProt or InterPro

Protein Sequence (300 amino acids)

>AO353_14840 NAD-dependent dehydratase (Pseudomonas fluorescens FW300-N2E3)
MHILLTGGTGLIGRQLCRHWLSQGHSLTVWSRRPEQVAKLCGTQVRGVRRLEDIGQRPVD
AVINLAGAPIADRLWTHRRKALLWNSRIRLTETLLAWLESLEQKPQLLISGSAVGWYGDG
GERELTEKSPPVSEDFASQLCIAWEETAQRAETLGIRVVLVRTGLVLSAEGGFLSRLLLP
FKLGLGGPIGNGRQWMPWIHIDDQIALIDFLLHQKDASGPYNACAPKPVRNREFAKTLAS
VLHRPAFMPMPSFVLKVGLGELSLLLLGGQRATPARLLAAGFTFRFTDLRAALDDVSSRL