Protein Info for AO353_14450 in Pseudomonas fluorescens FW300-N2E3
Annotation: hemin ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 87% identical to HMUV_PSEPF: Hemin import ATP-binding protein HmuV (hmuV) from Pseudomonas fluorescens (strain Pf0-1)
KEGG orthology group: K02013, iron complex transport system ATP-binding protein [EC: 3.6.3.34] (inferred from 89% identity to pfs:PFLU5227)Predicted SEED Role
"ABC-type hemin transport system, ATPase component" in subsystem Hemin transport system
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.34
Use Curated BLAST to search for 3.6.3.34
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A0N9WGJ3 at UniProt or InterPro
Protein Sequence (255 amino acids)
>AO353_14450 hemin ABC transporter ATP-binding protein (Pseudomonas fluorescens FW300-N2E3) MLRVENLQICRGKKIVLADIDLELKPGEVLGVLGPNGAGKSTLLGALCGELRPDHGRVWL DQRELSQWDGAQRAQRLAVLPQTSTLDFAFRVEEVVGMGRLPHQTGRVRDDEIVAAALQA ADVGHLSGRSYLALSGGERQRVHLARVLAQLWPGEAGQTLLLDEPTSMLDPLHQHTTLQA IREFADRGAAVLVILHDLNLAARYCDRILLLESGRPHALDTPQQVLRPEPLKAVFGLDVL VQPHPERGHPLIIAR