Protein Info for AO353_12105 in Pseudomonas fluorescens FW300-N2E3

Annotation: peptidase S41

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR00225: C-terminal processing peptidase" amino acids 63 to 384 (322 residues), 354.3 bits, see alignment E=3e-110 PF00595: PDZ" amino acids 108 to 176 (69 residues), 41.4 bits, see alignment E=3.2e-14 PF13180: PDZ_2" amino acids 109 to 180 (72 residues), 44.5 bits, see alignment E=3.1e-15 PF17820: PDZ_6" amino acids 124 to 178 (55 residues), 52.2 bits, see alignment 8.9e-18 PF03572: Peptidase_S41" amino acids 207 to 372 (166 residues), 196.1 bits, see alignment E=6.3e-62

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 95% identity to pfo:Pfl01_0331)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WHJ8 at UniProt or InterPro

Protein Sequence (439 amino acids)

>AO353_12105 peptidase S41 (Pseudomonas fluorescens FW300-N2E3)
MLHLSRLNSLALTIALVIGAPLAFAAQPAPAVAPAGTAATTKAPLPLEELRTFAEVMDRI
KAAYVEPVDDKTLLENAIKGMLSNLDPHSAYLGPEDFAELQESTSGEFGGLGIEVGAEDG
FIKVVSPIDDTPASKAGIQAGDFIVKINGQPTRGQSMTEAVDKMRGKIGEKITLTLVRDG
GAPFDVTLTRATIQVKSVKSQLLDSGYAYIRITQFQVKTGEEVSKALAKLRKDNGKKLSG
IVLDLRNNPGGVLQAAVEVVDHFITKGLIVYTKGRIANSELRFTATGKDESEAVPMVVLI
NGGSASASEIVAGALQDQKRAVVMGTTSFGKGSVQTVLPLNNDRALKITTALYFTPNGRS
IQAQGIVPDIEVRKAKITNEQDGEYFKEADLQGHLGNGNGGADKPTKSSGKAKPMPQDDD
YQLAQALSLLKGLSITRGH