Protein Info for AO353_10650 in Pseudomonas fluorescens FW300-N2E3

Annotation: DNA processing protein DprA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 transmembrane" amino acids 230 to 250 (21 residues), see Phobius details TIGR00732: DNA protecting protein DprA" amino acids 78 to 296 (219 residues), 253.8 bits, see alignment E=5e-80 PF02481: DNA_processg_A" amino acids 82 to 288 (207 residues), 248.3 bits, see alignment E=4.7e-78 PF17782: DprA_WH" amino acids 304 to 360 (57 residues), 30.2 bits, see alignment E=3.8e-11

Best Hits

KEGG orthology group: K04096, DNA processing protein (inferred from 87% identity to pfo:Pfl01_0019)

Predicted SEED Role

"Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9WHP1 at UniProt or InterPro

Protein Sequence (367 amino acids)

>AO353_10650 DNA processing protein DprA (Pseudomonas fluorescens FW300-N2E3)
MPLFAPTQVSPAELEARLRLHRLPELGPRRFQKLLEAFGSASKAISAPASAWRALGLPAA
CADARRSPLIRDGAYHALAWLEREGQYLLMVDQPGYPALLAEISDPPPLLFVAGDPGILE
KPQLAMVGSRRASRPGMDTATAFSRSLAGAGFVITSGLALGIDAAAHQAALDVGGQTVGV
LGTGLENFYPQRNRRIADAMIAQGSAVVSEFPLDAGPQASNFPRRNRIISGLSLGVLVVE
ASVASGSLITARLAAEQGREVYAIPGSIHHPGARGCHQLIRDGAVLVETIEHILEGLRGW
QNLPLSTETAAPVDHPLLCLLFAAPHTSEALADAAGWALPKVLAALTELEMEGRAVSEGG
RWFARVS