Protein Info for AO353_08545 in Pseudomonas fluorescens FW300-N2E3

Annotation: thiol-disulfide isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 194 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF20029: DUF6436" amino acids 127 to 185 (59 residues), 91 bits, see alignment E=2.3e-30

Best Hits

KEGG orthology group: None (inferred from 85% identity to pfl:PFL_5918)

Predicted SEED Role

"Thiol-disulfide isomerase and thioredoxins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0N9W459 at UniProt or InterPro

Protein Sequence (194 amino acids)

>AO353_08545 thiol-disulfide isomerase (Pseudomonas fluorescens FW300-N2E3)
MRPHYRTTLLASLLALVCAGVLWTAYDWFQGRYLRAFSSHTALFSGDPLNLPANLAGPGA
IRVVHFWDPACPCNVGNQQHLAELLEHFVPQGVEFYAVQKPGSQGQLPSTLSRLKTLDTL
PGSEQIPASPAVAIWDRSGKLAYFGPYSEGLTCNSSNSFIEPILQALSEDRPVSATHTLA
VGCYCPWAKTDDAH